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A3PNP4 (A3PNP4_RHOS1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Rsph17029_2858
OrganismRhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) [Complete proteome] [HAMAP]
Taxonomic identifier349101 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length377 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2441Iron By similarity HAMAP MF_00323
Metal binding3251Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
A3PNP4 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: 262885529923749F

FASTA37742,580
        10         20         30         40         50         60 
MSGSGMTPML QATPEQARTL GAEEPIRPGQ DRLAHAPADH PELPQPKIGI LLANLGTPDN 

        70         80         90        100        110        120 
YDYWSMRRYL NEFLSDKRVI DYPAWKWQPL LQILILSKRP FSSGANYKLI WNHDKGESPL 

       130        140        150        160        170        180 
MTITKDQTAA IAAEIRSLYG NRVMVDFCMR YGNPSTESRV RAMVEAGCEK ILFFPLYPHY 

       190        200        210        220        230        240 
AGATSATAND EFFRAMMKEK RQPAVRTVPE YYDNPLYIDA LAQSVERAYA QLDHRPDVLV 

       250        260        270        280        290        300 
ASYHGMPKRY LMAGDPYHCQ CAKTSRLLRE RLGWEKGAID TTFQSVFGPE EWLKPYTVEH 

       310        320        330        340        350        360 
VAELARAGKK RIAVIAPAFS ADCIETLEEI NGEIREAFEE AGGEEFTYIP CLNDDEAHIR 

       370 
ALVSVIEDNL AGWLARG

« Hide

References

[1]"Complete sequence of chromosome 1 of Rhodobacter sphaeroides ATCC 17029."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P., Mackenzie C., Choudhary M., Donohue T.J., Kaplan S.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000577 Genomic DNA. Translation: ABN77960.1.
RefSeqYP_001044732.1. NC_009049.1.

3D structure databases

ProteinModelPortalA3PNP4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA3PNP4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4897575.
GenomeReviewsGene locus Rsph17029_2858 in contig CP000577_GR.
KEGGrsh:Rsph17029_2858.
PATRIC23173639. VBIRhoSph114483_3106.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMATIEEIGM.
ProtClustDBPRK00035.

Enzyme and pathway databases

BioCycRSPH349101:RSPH17029_2858-MONOMER.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA3PNP4_RHOS1
AccessionPrimary (citable) accession number: A3PNP4
Entry history
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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