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A3PNI1 (A3PNI1_RHOS1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase 2 HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase 2 HAMAP MF_00315
Gene names
Name:dxs2 HAMAP MF_00315
Ordered Locus Names:Rsph17029_2795
OrganismRhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) [Complete proteome] [HAMAP]
Taxonomic identifier349101 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length637 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315 SAAS SAAS005477

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS005477

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS005477

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS005477

Subunit structure

Homodimer By similarity. HAMAP MF_00315 SAAS SAAS005477

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
A3PNI1 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: 7F48C4BFF93C2592

FASTA63767,562
        10         20         30         40         50         60 
MTDRPCTPTL DRVTLPVDMK GLTDRELRSL ADELRAETIS AVSVTGGHLG AGLGVVELTV 

        70         80         90        100        110        120 
ALHAVFDAPR DKIIWDVGHQ CYPHKILTGR RDRIRTLRQG GGLSGFTKRS ESPYDCFGAG 

       130        140        150        160        170        180 
HSSTSISAAV GFAAAREMGG DTGDAVAVIG DGSMSAGMAF EALNHGGHLK NRVIVILNDN 

       190        200        210        220        230        240 
EMSIAPPVGA LSSYLSRLYA GAPFQDFKAA AKGALGLLPE PFQEGARRAK EMLKSVTVGG 

       250        260        270        280        290        300 
TLFEELGFSY VGPIDGHDLD QLLPVLRTVK QRAHAPVLIH VITKKGRGYA PAEAARDRGH 

       310        320        330        340        350        360 
ATNKFNVLTG AQVKPVSNAP SYTKVFAQSL IKEAEVDERI CAVTAAMPDG TGLNLFGERF 

       370        380        390        400        410        420 
PKRTFDVGIA EQHAVTFSAA LAAGGMRPFC AIYSTFLQRG YDQIVHDVAI QRLPVRFAID 

       430        440        450        460        470        480 
RAGLVGADGA THAGSFDVAF LSNLPGIVVM AAADEAELVH MVATAAAHDE GPIAFRYPRG 

       490        500        510        520        530        540 
DGVGVEMPAK GVPLQIGRGR VVREGTRIAL LSFGTRLAEV QVAAEALAAR GISPTVADAR 

       550        560        570        580        590        600 
FAKPLDRDLI LQLAAHHEAL ITIEEGAIGG FGSHVAQLLA EAGVFDRGFR YRSMVLPDTF 

       610        620        630 
IDHNSAEVMY ATAGLNAADI ERKALETLGV EVLARRA

« Hide

References

[1]"Complete sequence of chromosome 1 of Rhodobacter sphaeroides ATCC 17029."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P., Mackenzie C., Choudhary M., Donohue T.J., Kaplan S.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000577 Genomic DNA. Translation: ABN77897.1.
RefSeqYP_001044669.1. NC_009049.1.

3D structure databases

ProteinModelPortalA3PNI1.
ModBaseSearch...

Protein-protein interaction databases

STRINGA3PNI1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4896646.
GenomeReviewsGene locus Rsph17029_2795 in contig CP000577_GR.
KEGGrsh:Rsph17029_2795.
PATRIC23173509. VBIRhoSph114483_3042.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1154.
HOGENOMHBG571647.
OMAEAMNAHA.
ProtClustDBPRK05444.

Enzyme and pathway databases

BioCycRSPH349101:RSPH17029_2795-MONOMER.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR005477. Dxylulose-5-P_synthase.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA3PNI1_RHOS1
AccessionPrimary (citable) accession number: A3PNI1
Entry history
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info