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A3PJF0 (DER_RHOS1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTPase Der
Alternative name(s):
GTP-binding protein EngA
Gene names
Name:der
Synonyms:engA
Ordered Locus Names:Rsph17029_1356
OrganismRhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) [Complete proteome] [HAMAP]
Taxonomic identifier349101 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length487 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

GTPase that plays an essential role in the late steps of ribosome biogenesis By similarity. HAMAP MF_00195

Subunit structure

Associates with the 50S ribosomal subunit By similarity.

Sequence similarities

Belongs to the Era/MnmE GTP-binding protein family. Der subfamily.

Contains 2 G (guanine nucleotide-binding) domains.

Contains 1 KH-like domain.

Ontologies

Keywords
   Biological processRibosome biogenesis
   DomainRepeat
   LigandGTP-binding
Nucleotide-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processribosome biogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentintracellular

Inferred from electronic annotation. Source: InterPro

   Molecular functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 487487GTPase Der HAMAP MF_00195
PRO_1000011720

Regions

Domain14 – 120107G 1
Domain214 – 322109G 2
Domain378 – 46386KH-like
Nucleotide binding9 – 168GTP 1 Potential
Nucleotide binding56 – 605GTP 1 Potential
Nucleotide binding119 – 1224GTP 1 Potential
Nucleotide binding209 – 2168GTP 2 Potential
Nucleotide binding256 – 2605GTP 2 Potential
Nucleotide binding321 – 3244GTP 2 Potential

Sequences

Sequence LengthMass (Da)Tools
A3PJF0 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: 7CB77D4ED04330E0

FASTA48754,121
        10         20         30         40         50         60 
MSFTLAIVGR PNVGKSTLFN RLVGKRLALV DDQPGVTRDL REGDARLIDL RFTVIDTAGL 

        70         80         90        100        110        120 
EEVTDDSLQG RMRRLTERAV EMADVCLFLI DGRVGVTPSD EVFADILRRK NAHVILGVNK 

       130        140        150        160        170        180 
AEGRAGDGGA IEAWSLGLGE PIRLSAEHGE GMDDLYHILR PIAEGFAERA AADAPVVDVD 

       190        200        210        220        230        240 
VPEEEADLEA DPEAHKPTVK HPLQIAVIGR PNAGKSTLIN KIIGEDRLLT GPEAGITRDA 

       250        260        270        280        290        300 
ISVRSEWHGT PIRIFDTAGM RKKARISDKL EKLSVADGLR AVRFAEVVVV LLDVEIPFEQ 

       310        320        330        340        350        360 
QDLRIADFAE TEGRAVVVAV NKWDLEGEKQ EKLAELKEMF ERLLPQLRGA PLVTVSAKTG 

       370        380        390        400        410        420 
RGLDRLHAAI LRAHDIWNRR ITTARLNTWL GAMVEAHPPP APGGRRIKLR YMTQVKTRPP 

       430        440        450        460        470        480 
GFVVMCSHPD EMPDSYRRYL VNGLRDHFDM PGTPIRLTMR GQGDKNPFKE RKFRTPSRLR 


KHLGKKD

« Hide

References

[1]"Complete sequence of chromosome 1 of Rhodobacter sphaeroides ATCC 17029."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P., Mackenzie C., Choudhary M., Donohue T.J., Kaplan S.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17029 / ATH 2.4.9.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000577 Genomic DNA. Translation: ABN76466.1.
RefSeqYP_001043238.1. NC_009049.1.

3D structure databases

ProteinModelPortalA3PJF0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA3PJF0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4896835.
GenomeReviewsGene locus Rsph17029_1356 in contig CP000577_GR.
KEGGrsh:Rsph17029_1356.
PATRIC23170467. VBIRhoSph114483_1543.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1160.
HOGENOMHBG592135.
OMALAVNKCE.
ProtClustDBPRK00093.

Enzyme and pathway databases

BioCycRSPH349101:RSPH17029_1356-MONOMER.

Family and domain databases

HAMAPMF_00195. GTPase_Der.
[Tree]
InterProIPR016484. GTP-bd_EngA.
IPR006073. GTP_binding_domain.
IPR015946. KH_dom-like_a/b.
IPR005225. Small_GTP-bd_dom.
[Graphical view]
Gene3DG3DSA:3.30.300.20. KH_prok. 1 hit.
KOK03977.
PANTHERPTHR11649:SF5. PTHR11649:SF5. 1 hit.
PfamPF01926. MMR_HSR1. 2 hits.
[Graphical view]
PIRSFPIRSF006485. GTP-binding_EngA. 1 hit.
PRINTSPR00326. GTP1OBG.
TIGRFAMsTIGR03594. GTPase_EngA. 1 hit.
TIGR00231. Small_GTP. 2 hits.
ProtoNetSearch...

Entry information

Entry nameDER_RHOS1
AccessionPrimary (citable) accession number: A3PJF0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 3, 2007
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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