ID   A3PIM1_CERS1            Unreviewed;       533 AA.
AC   A3PIM1;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   27-MAR-2024, entry version 85.
DE   RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE            EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN   ORFNames=Rsph17029_1076 {ECO:0000313|EMBL:ABN76187.1};
OS   Cereibacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) (Rhodobacter
OS   sphaeroides).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Cereibacter.
OX   NCBI_TaxID=349101 {ECO:0000313|EMBL:ABN76187.1};
RN   [1] {ECO:0000313|EMBL:ABN76187.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 17029 {ECO:0000313|EMBL:ABN76187.1};
RX   PubMed=17172323;
RA   Choudhary M., Zanhua X., Fu Y.X., Kaplan S.;
RT   "Genome analyses of three strains of Rhodobacter sphaeroides: evidence of
RT   rapid evolution of chromosome II.";
RL   J. Bacteriol. 189:1914-1921(2007).
RN   [2] {ECO:0000313|EMBL:ABN76187.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 17029 {ECO:0000313|EMBL:ABN76187.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.,
RA   Mackenzie C., Choudhary M., Donohue T.J., Kaplan S.;
RT   "Complete sequence of Chromosome1 of Rhodobacter sphaeroides ATCC 17029.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC         (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC         diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR   EMBL; CP000577; ABN76187.1; -; Genomic_DNA.
DR   AlphaFoldDB; A3PIM1; -.
DR   KEGG; rsh:Rsph17029_1076; -.
DR   HOGENOM; CLU_005138_6_2_5; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR   CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR   Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR   PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR   PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   SUPFAM; SSF117018; ATP-dependent DNA ligase DNA-binding domain; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ABN76187.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          302..433
FT                   /note="ATP-dependent DNA ligase family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50160"
SQ   SEQUENCE   533 AA;  58974 MW;  2FF725E138390678 CRC64;
     MKRFAALFDL LDRTTRTSAK VAALADYFRT APEEDRVWTI GLLSGRRPKR AVNTTELRSW
     AAEASGLPVW LAEEVHPIVG DLAETISLLL PEPSQTSDRT LDGWMRELVS LTGRPAEVRR
     AAILDAWDRL STPERFLFNK LITGGFRMGV SQGLMTRALA QATGVDEAVL AHRLMGDWKP
     GRIGFETLIG AHDPEADASK PYPFALASPV EEVAALGDPA DWLAEWKWDG IRGQLVNRAG
     AFALWSRGEE LVTDRFPDLA PLRDFLPPGL VIDAEVLAWG GDGPLPFAAL QKRIGRLTVP
     KKILAEAPAH LLAYDLLEEN GEDLRAAPLA HRRARLEAVL AALPPGVPIS PSPLVAFDDW
     ETLGGIRATA REKIAEGLML KRASSPYFVG RKRGDWWKWK LDPYTVDAVM LYAQQGAGRR
     ATLFTDFTFG VRDGDDLVPF TKAYSGLTDA EFRQITDWVR KNTLERFGPV RRVPPELVFE
     LAFEGIQASP RHKSGIALRF PRMVRWRKDK PAAEIDTLES LRELLAATGG AAP
//