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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExonuclease, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:Rsph17029_0494
OrganismiRhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)
Taxonomic identifieri349101 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
Proteomesi
  • UP000002606 Componenti: Chromosome 1

Subcellular locationi

A3PGZ4:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003038151 – 519Exodeoxyribonuclease 7 large subunitAdd BLAST519

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Structurei

3D structure databases

SMRiA3PGZ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229266.
KOiK03601.
OMAiLVWPVKV.

Family and domain databases

CDDicd04489. ExoVII_LU_OBF. 1 hit.
HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiView protein in InterPro
IPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
PANTHERiPTHR30008. PTHR30008. 1 hit.
PfamiView protein in Pfam
PF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

A3PGZ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDLFEDPAP SRNTPEFTVS ELSGAVKRVI EGEFGLVRVR GEIGRVSRPA
60 70 80 90 100
SGHLYFDLKD DRAVMAAICW KGQAGRLSVR PEEGMEVVAT GRMTTFPGQS
110 120 130 140 150
KYQIIVEDMA PAGAGALMAM LEKRRAALAA EGLFDAGRKR PLPFLPRVIG
160 170 180 190 200
VVTSPSGAVI RDILHRLRDR FPSHVLIWPV AVQGEKCAPE VAAAIRGFNT
210 220 230 240 250
LPEGGPIPRP DLLIVARGGG SLEDLWGFNE EIVVRAAAES RIPLISAVGH
260 270 280 290 300
ETDTTLIDHA ADRRAPTPTA AAEMAVPVRL ELLAGLDGQG ARLSRCAAET
310 320 330 340 350
IRRRDQRLRD LARALPRLES LVAGPSQRFD LWSGRLSGAL GQSVAARRAR
360 370 380 390 400
LEPLGAHLRP RLLADLVARQ KDRLGDRTRS LETCLGRRAE RARDRFDALS
410 420 430 440 450
ARLAPAFARL IAETERASRR DAATLGTLAA RLDAAPEARL ARLSDRLEAL
460 470 480 490 500
DRLRQTLGYR ETLKRGYAVV RADGAVLTTK AEAGAAAMLE IEFQDGRLSV
510
GRGKTRKPKE EPPAQGSLL
Length:519
Mass (Da):56,309
Last modified:April 3, 2007 - v1
Checksum:i05859DFB9B17EE5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000577 Genomic DNA. Translation: ABN75610.1.
RefSeqiWP_011840393.1. NC_009049.1.

Genome annotation databases

EnsemblBacteriaiABN75610; ABN75610; Rsph17029_0494.
KEGGirsh:Rsph17029_0494.

Similar proteinsi

Entry informationi

Entry nameiEX7L_RHOS1
AccessioniPrimary (citable) accession number: A3PGZ4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: April 3, 2007
Last modified: October 25, 2017
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families