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Protein

Uridine kinase

Gene

P9301_10701

Organism
Prochlorococcus marinus (strain MIT 9301)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + cytidine = ADP + CMP.UniRule annotation
ATP + uridine = ADP + UMP.UniRule annotation

Pathway: CTP biosynthesis via salvage pathway

This protein is involved in step 1 of the subpathway that synthesizes CTP from cytidine.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Uridine kinase (P9301_10701)
  2. no protein annotated in this organism
  3. no protein annotated in this organism
This subpathway is part of the pathway CTP biosynthesis via salvage pathway, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CTP from cytidine, the pathway CTP biosynthesis via salvage pathway and in Pyrimidine metabolism.

Pathway: UMP biosynthesis via salvage pathway

This protein is involved in step 1 of the subpathway that synthesizes UMP from uridine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Uridine kinase (P9301_10701)
This subpathway is part of the pathway UMP biosynthesis via salvage pathway, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes UMP from uridine, the pathway UMP biosynthesis via salvage pathway and in Pyrimidine metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMAR167546:GH1Y-1098-MONOMER.
UniPathwayiUPA00574; UER00637.
UPA00579; UER00640.

Names & Taxonomyi

Protein namesi
Recommended name:
Uridine kinaseUniRule annotation (EC:2.7.1.48UniRule annotation)
Gene namesi
Ordered Locus Names:P9301_10701Imported
OrganismiProchlorococcus marinus (strain MIT 9301)Imported
Taxonomic identifieri167546 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000001430 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi167546.P9301_10701.

Structurei

3D structure databases

ProteinModelPortaliA3PD68.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uridine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0572.
HOGENOMiHOG000232888.
KOiK00876.
OMAiTDNYYKT.
OrthoDBiEOG6PCPXK.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR006083. PRK/URK.
IPR026008. Uridine_kinase_.
IPR000764. Uridine_kinase_like.
[Graphical view]
PANTHERiPTHR10285:SF6. PTHR10285:SF6. 1 hit.
PfamiPF00485. PRK. 1 hit.
[Graphical view]
PRINTSiPR00988. URIDINKINASE.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

A3PD68-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLILISGPS GSGKTTLSNQ IIKKIKNGIV LSTDNYYKTG LISKLLSKFV
60 70 80 90 100
EGFFDRSISF NNKLFKKDFD FIYMNGISIC KRYYNFEKKS IQNILNETNN
110 120 130 140 150
ISFIIVEGIF AKEISNTLNN KDYIFLEIKT KKNECMKRVV QRDIKERGKD
160 170 180 190
KKQAENDFLK SWSIYYEKFK PNSQKNNTNK FIIKKNTDID PILKKLFN
Length:198
Mass (Da):23,193
Last modified:April 3, 2007 - v1
Checksum:i986B558DF38D7B49
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000576 Genomic DNA. Translation: ABO17693.1.
RefSeqiWP_011863034.1. NC_009091.1.
YP_001091294.1. NC_009091.1.

Genome annotation databases

EnsemblBacteriaiABO17693; ABO17693; P9301_10701.
GeneIDi4912811.
KEGGipmg:P9301_10701.
PATRICi22995697. VBIProMar103344_1033.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000576 Genomic DNA. Translation: ABO17693.1.
RefSeqiWP_011863034.1. NC_009091.1.
YP_001091294.1. NC_009091.1.

3D structure databases

ProteinModelPortaliA3PD68.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi167546.P9301_10701.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABO17693; ABO17693; P9301_10701.
GeneIDi4912811.
KEGGipmg:P9301_10701.
PATRICi22995697. VBIProMar103344_1033.

Phylogenomic databases

eggNOGiCOG0572.
HOGENOMiHOG000232888.
KOiK00876.
OMAiTDNYYKT.
OrthoDBiEOG6PCPXK.

Enzyme and pathway databases

UniPathwayiUPA00574; UER00637.
UPA00579; UER00640.
BioCyciPMAR167546:GH1Y-1098-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR006083. PRK/URK.
IPR026008. Uridine_kinase_.
IPR000764. Uridine_kinase_like.
[Graphical view]
PANTHERiPTHR10285:SF6. PTHR10285:SF6. 1 hit.
PfamiPF00485. PRK. 1 hit.
[Graphical view]
PRINTSiPR00988. URIDINKINASE.
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MIT 9301Imported.

Entry informationi

Entry nameiA3PD68_PROM0
AccessioniPrimary (citable) accession number: A3PD68
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: May 27, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.