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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Prochlorococcus marinus (strain MIT 9301)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciPMAR167546:G1G8B-268-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:P9301_02731
OrganismiProchlorococcus marinus (strain MIT 9301)
Taxonomic identifieri167546 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000001430 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000106251 – 198Peptidyl-tRNA hydrolaseAdd BLAST198

Proteomic databases

PRIDEiA3PAX1

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi167546.P9301_02731

Structurei

3D structure databases

ProteinModelPortaliA3PAX1
SMRiA3PAX1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZPD Bacteria
COG0193 LUCA
HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH
OrthoDBiPOG091H02CU

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

A3PAX1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHEIYLIGLG NPGKKYYNSR HNIGFLLLEK LSKKYNSNFL LKDKLKSSCS
60 70 80 90 100
EFQINNYTFR LFLPNTFMNN SGYAVRAIVD WYKVNLDQIF IIVDDKDLPL
110 120 130 140 150
GKIRFRRKGS SGGHNGLKSI IEQLQSQNFK RIRIGIGSPP LIKGENNFNT
160 170 180 190
ISHVLGNISL EEKLILDKVF KRVIESLEHL NTKKEDHIIN ELNSFNQD
Length:198
Mass (Da):22,901
Last modified:April 3, 2007 - v1
Checksum:iD02EA760F4E0AE19
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000576 Genomic DNA Translation: ABO16896.1
RefSeqiWP_011862294.1, NC_009091.1

Genome annotation databases

EnsemblBacteriaiABO16896; ABO16896; P9301_02731
GeneIDi4912770
KEGGipmg:P9301_02731

Similar proteinsi

Entry informationi

Entry nameiPTH_PROM0
AccessioniPrimary (citable) accession number: A3PAX1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 3, 2007
Last modified: May 23, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health