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Protein

tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

Gene

mnmG

Organism
Burkholderia pseudomallei (strain 1106a)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.UniRule annotation

Cofactori

FADUniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 18FADUniRule annotation6
Nucleotide bindingi274 – 288NADUniRule annotationAdd BLAST15

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

FAD, Flavoprotein, NAD

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGUniRule annotation
Alternative name(s):
Glucose-inhibited division protein AUniRule annotation
Gene namesi
Name:mnmGUniRule annotation
Synonyms:gidAUniRule annotation
Ordered Locus Names:BURPS1106A_4056
OrganismiBurkholderia pseudomallei (strain 1106a)
Taxonomic identifieri357348 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
Proteomesi
  • UP000006738 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000165661 – 657tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGAdd BLAST657

Interactioni

Subunit structurei

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA3P104.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MnmG family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000201060.
KOiK03495.
OMAiFRPGYAI.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00129. MnmG_GidA. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR026904. GidA-assoc_3.
IPR004416. MnmG.
IPR002218. MnmG-rel.
IPR020595. MnmG-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3P104-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYPTEFDVI VVGGGHAGTE AALASARMGA KTLLLTHNIE TLGQMSCNPS
60 70 80 90 100
IGGIGKGHLV KEVDALGGAM AAATDEGGIQ FRILNSSKGP AVRATRAQAD
110 120 130 140 150
RVLYKQAIRR RLENQPNLWL FQQAVDDLMV EGDRVVGAVT QVGVRFRARA
160 170 180 190 200
VVLTAGTFLD GKIHVGLNHY TGGRAGDPAA VSLSSRLKEL NLPQGRLKTG
210 220 230 240 250
TPPRIDGRTI DFSKLDEQPG DLDPIPVFSF LGRAEQHPQQ LPCWVTHTNE
260 270 280 290 300
RTHDIIRSGL DRSPMYTGVI EGVGPRYCPS IEDKIHRFAS KDSHQIFLEP
310 320 330 340 350
EGLTTNEFYP NGISTSLPFD VQLALVHSMR GLEQAHILRP GYAIEYDYFD
360 370 380 390 400
PRALKSSLET KAIGGLFFAG QINGTTGYEE AAAQGLLAGI NAGRYAQEKD
410 420 430 440 450
AWCPRRDQAY LGVLVDDLVT RGVSEPYRMF TSRAEYRLSL REDNADMRLT
460 470 480 490 500
EIGRELGVVD DVRWDAFNRK RDAVSRETER LRTTWVTPKT LPADEATALL
510 520 530 540 550
GKPIDHEYSL AELLRRPGVS YDGVCGLRGG ECGPSEPLAE DELLLAQIKE
560 570 580 590 600
QIEIGIKYQG YIERQAGEIE RNGANENTRL PDGIDYTEVR GLSFEVSQKL
610 620 630 640 650
NQFRPETIGQ ASRISGMTPA AISLLMVHLK KRGLGRRKGA DSVPGADVQA

DNTAAQQ
Length:657
Mass (Da):71,981
Last modified:April 3, 2007 - v1
Checksum:iE75CD490ADDDE67E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000572 Genomic DNA. Translation: ABN88815.1.
RefSeqiWP_004195816.1. NC_009076.1.

Genome annotation databases

EnsemblBacteriaiABN88815; ABN88815; BURPS1106A_4056.
KEGGibpl:BURPS1106A_4056.
PATRICi19226375. VBIBurPse14980_3813.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000572 Genomic DNA. Translation: ABN88815.1.
RefSeqiWP_004195816.1. NC_009076.1.

3D structure databases

ProteinModelPortaliA3P104.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABN88815; ABN88815; BURPS1106A_4056.
KEGGibpl:BURPS1106A_4056.
PATRICi19226375. VBIBurPse14980_3813.

Phylogenomic databases

HOGENOMiHOG000201060.
KOiK03495.
OMAiFRPGYAI.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00129. MnmG_GidA. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR026904. GidA-assoc_3.
IPR004416. MnmG.
IPR002218. MnmG-rel.
IPR020595. MnmG-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMNMG_BURP0
AccessioniPrimary (citable) accession number: A3P104
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 3, 2007
Last modified: November 2, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.