A3NYT6 (A3NYT6_BURP0) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase WcbS EMBL ABN88989.1
EC=3.5.1.- EMBL ABN88989.1

Gene names

Name:	wcbS EMBL ABN88989.1
Ordered Locus Names:	BURPS1106A_3270

Organism

Burkholderia pseudomallei (strain 1106a) [Complete proteome] [HAMAP]

Taxonomic identifier

357348 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870 EMBL ABN88989.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A3NYT6 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: F5CDAEC457367B70	FASTA	305	33,141
	10 20 30 40 50 60 MSVPTGWATS QGTLARALTI DGHGLHTGRR VGVRILPARP EDGVTGIAFR RVEQGRTLAT 70 80 90 100 110 120 LPVDPALRRA QPLCTMLRNA DGVGVRTVEH LLASLLACEI DHAIVELDAE EVPILDGSAT 130 140 150 160 170 180 PWVDAIRTCG RVALDAPKRF IRVLRTVVVT EGEGEQRREM RIEPAPRYEL SVRNDLRGFG 190 200 210 220 230 240 EMHWDGALTP AAFATEIAPS RSYGRVKWAV PAILAGYLRG VPILRGARPS CTASIVGKRV 250 260 270 280 290 300 LGGMRLPDEF VRHRVLDLVG DLALAGAPLL ARVSAVRPSH EMNFRLVDAL LAEPGAWQWA DFSEA

References

[1]	DeShazer D., Woods D.E., Nierman W.C. Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000572 Genomic DNA. Translation: ABN88989.1.
RefSeq	YP_001067507.1. NC_009076.1.
3D structure databases
ProteinModelPortal	A3NYT6.
ModBase	Search...
Protein-protein interaction databases
STRING	A3NYT6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4902978.
GenomeReviews	Gene locus BURPS1106A_3270 in contig CP000572_GR.
KEGG	bpl:BURPS1106A_3270.
PATRIC	19224881. VBIBurPse14980_3084.
TIGR	BURPS1106A_3270.
Phylogenomic databases
eggNOG	COG0774.
HOGENOM	HBG482342.
OMA	IAFRRVA.
ProtClustDB	PRK13187.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KO	K02535.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
ProtoNet	Search...

Entry information

Entry name

A3NYT6_BURP0

Accession

Primary (citable) accession number: A3NYT6

Entry history

Integrated into UniProtKB/TrEMBL:	April 3, 2007
Last sequence update:	April 3, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)