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A3NYA9 (UPPP2_BURP0) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 2

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 2
Undecaprenyl pyrophosphate phosphatase 2
Gene names
Name:uppP2
Ordered Locus Names:BURPS1106A_3092
OrganismBurkholderia pseudomallei (strain 1106a) [Complete proteome] [HAMAP]
Taxonomic identifier357348 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 276276Undecaprenyl-diphosphatase 2 HAMAP-Rule MF_01006
PRO_0000303024

Regions

Transmembrane85 – 10521Helical; Potential
Transmembrane108 – 12821Helical; Potential
Transmembrane187 – 20721Helical; Potential
Transmembrane217 – 23721Helical; Potential
Transmembrane253 – 27321Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
A3NYA9 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: 608BFAFD49296177

FASTA27630,284
        10         20         30         40         50         60 
MDWILICKAL ALGIVEGLTE FLPVSSTGHL IVAGSFLRFH PEQAKTFDVV IQFGAILAVC 

        70         80         90        100        110        120 
WEYRRRIIDV VTGLPAQREA RRFTMNVVIA TVPAVALALL FEKTIKSVLF APVPVAVALV 

       130        140        150        160        170        180 
VGGAAILWVE GRQRERSEPA RVQSIDALTP FDALKVGLAQ CCALIPGMSR SGSTIIGGML 

       190        200        210        220        230        240 
FGLERRVATE FSFFLAIPVI FGATLYETAK DWRAFNVDSV GLFAIGLVAA FVSAFACVRW 

       250        260        270 
LLRYVASHDF TAFAWYRIAF GLFVLLVGYS GWIEWT 

« Hide

References

[1]DeShazer D., Woods D.E., Nierman W.C.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1106a.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000572 Genomic DNA. Translation: ABN90854.1.
RefSeqYP_001067330.1. NC_009076.1.

3D structure databases

ProteinModelPortalA3NYA9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING357348.BURPS1106A_3092.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABN90854; ABN90854; BURPS1106A_3092.
GeneID4900188.
KEGGbpl:BURPS1106A_3092.
PATRIC19224534. VBIBurPse14980_2912.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAWRKISSS.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycBPSE357348:GHVF-3092-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP2_BURP0
AccessionPrimary (citable) accession number: A3NYA9
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: April 3, 2007
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families