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A3NSB9 (A3NSB9_BURP0) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446
EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL ABN90528.1
Ordered Locus Names:BURPS1106A_0960
OrganismBurkholderia pseudomallei (strain 1106a) [Complete proteome] [HAMAP]
Taxonomic identifier357348 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group ›

Protein attributes

Sequence length419 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
A3NSB9 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: F85E7112F2CB3C69

FASTA41946,146
        10         20         30         40         50         60 
MPYQHIKVPE GGDKITVNKD FSLNVSDQPI IPYIEGDGTG FDITPVMIKV VDAAVEKAYG 

        70         80         90        100        110        120 
GKKKIHWMEI YAGEKATKVY GPDVWLPEET LQVLKEYVVS IKGPLTTPVG GGIRSLNVAL 

       130        140        150        160        170        180 
RQELDLYVCL RPIQYFKGVP SPVREPEKTN MVIFRENSED IYAGIEWAAE SEQAKKVIKF 

       190        200        210        220        230        240 
LQEEMGVKKI RFPQTSGIGI KPVSKEGTER LVRKAIQYAI DNDRKSVTLV HKGNIMKFTE 

       250        260        270        280        290        300 
GAFRDAGYAL AQKEFGAELI DGGPWMKFKN PKTGNEIVVK DSIADAFLQQ ILLRPAEYDV 

       310        320        330        340        350        360 
IATLNLNGDY ISDALAAQVG GIGIAPGANL SDSVAMFEAT HGTAPKYAGK DYVNPGSEIL 

       370        380        390        400        410 
SAEMMLRHLG WTEAADVIIS AMEKSIKQKR VTYDFARLME GATQVSCSGF GQVLIENME

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References

[1]DeShazer D., Woods D.E., Nierman W.C.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1106a.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000572 Genomic DNA. Translation: ABN90528.1.
RefSeqYP_001065240.1. NC_009076.1.

3D structure databases

ProteinModelPortalA3NSB9.
SMRA3NSB9. Positions 6-418.
ModBaseSearch...

Protein-protein interaction databases

STRING357348.BURPS1106A_0960.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABN90528; ABN90528; BURPS1106A_0960.
GeneID4899455.
KEGGbpl:BURPS1106A_0960.
PATRIC19220468. VBIBurPse14980_0918.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0538.
HOGENOMHOG000021113.
KOK00031.
OMAFRDWGYE.
ProtClustDBPRK07006.

Enzyme and pathway databases

BioCycBPSE357348:GHVF-4188-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA3NSB9_BURP0
AccessionPrimary (citable) accession number: A3NSB9
Entry history
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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