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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Burkholderia pseudomallei (strain 1106a)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciBPSE357348:GHVF-582-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:BURPS1106A_0583
OrganismiBurkholderia pseudomallei (strain 1106a)
Taxonomic identifieri357348 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
Proteomesi
  • UP000006738 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 201201Peptidyl-tRNA hydrolasePRO_1000010574Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA3NR95.
SMRiA3NR95. Positions 2-199.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000004796.
KOiK01056.
OMAiFMNRSGL.
OrthoDBiEOG6C5RTR.

Family and domain databases

Gene3Di3.40.50.1470. 1 hit.
HAMAPiMF_00083. Pept_tRNA_hydro_bact.
InterProiIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
PANTHERiPTHR17224. PTHR17224. 1 hit.
PfamiPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
SUPFAMiSSF53178. SSF53178. 1 hit.
TIGRFAMsiTIGR00447. pth. 1 hit.
PROSITEiPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3NR95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKLIVGLGN PGAEYTATRH NAGFWLVDQL AREAGATLRD ERRFHGFYAK
60 70 80 90 100
ARLFGEEVHL LEPQTYMNRS GQAVVALAHF FKILPTEILV AHDELDLPPG
110 120 130 140 150
AAKLKLGGGS GGHNGLKDIS AHLSSQQYWR LRIGIGHPRD LIPESARAGA
160 170 180 190 200
KPDVANFVLK PPRKDEQDLI DAAIERALAV MPTAIKGETE RAMMQLHRNG

A
Length:201
Mass (Da):22,026
Last modified:April 3, 2007 - v1
Checksum:i8AB2EBFDFED77598
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000572 Genomic DNA. Translation: ABN90851.1.
RefSeqiWP_004202941.1. NC_009076.1.

Genome annotation databases

EnsemblBacteriaiABN90851; ABN90851; BURPS1106A_0583.
KEGGibpl:BURPS1106A_0583.
PATRICi19219742. VBIBurPse14980_0557.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000572 Genomic DNA. Translation: ABN90851.1.
RefSeqiWP_004202941.1. NC_009076.1.

3D structure databases

ProteinModelPortaliA3NR95.
SMRiA3NR95. Positions 2-199.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABN90851; ABN90851; BURPS1106A_0583.
KEGGibpl:BURPS1106A_0583.
PATRICi19219742. VBIBurPse14980_0557.

Phylogenomic databases

HOGENOMiHOG000004796.
KOiK01056.
OMAiFMNRSGL.
OrthoDBiEOG6C5RTR.

Enzyme and pathway databases

BioCyciBPSE357348:GHVF-582-MONOMER.

Family and domain databases

Gene3Di3.40.50.1470. 1 hit.
HAMAPiMF_00083. Pept_tRNA_hydro_bact.
InterProiIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
PANTHERiPTHR17224. PTHR17224. 1 hit.
PfamiPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
SUPFAMiSSF53178. SSF53178. 1 hit.
TIGRFAMsiTIGR00447. pth. 1 hit.
PROSITEiPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. DeShazer D., Woods D.E., Nierman W.C.
    Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1106a.

Entry informationi

Entry nameiPTH_BURP0
AccessioniPrimary (citable) accession number: A3NR95
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 3, 2007
Last modified: December 9, 2015
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.