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A3NEF8

- IF12_BURP6

UniProt

A3NEF8 - IF12_BURP6

Protein

Translation initiation factor IF-1 2

Gene

infA2

Organism
Burkholderia pseudomallei (strain 668)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3.UniRule annotation

    GO - Molecular functioni

    1. translation initiation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Enzyme and pathway databases

    BioCyciBPSE320373:GJ9C-3717-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor IF-1 2UniRule annotation
    Gene namesi
    Name:infA2UniRule annotation
    Ordered Locus Names:BURPS668_3725
    OrganismiBurkholderia pseudomallei (strain 668)
    Taxonomic identifieri320373 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
    ProteomesiUP000002153: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 7272Translation initiation factor IF-1 2PRO_0000338786Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi320373.BURPS668_3725.

    Structurei

    3D structure databases

    ProteinModelPortaliA3NEF8.
    SMRiA3NEF8. Positions 2-72.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 7272S1-likeUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the IF-1 family.UniRule annotation
    Contains 1 S1-like domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0361.
    HOGENOMiHOG000221323.
    KOiK02518.
    OMAiMQGEVTE.
    OrthoDBiEOG6384SC.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    HAMAPiMF_00075. IF_1.
    InterProiIPR012340. NA-bd_OB-fold.
    IPR022967. RNA-binding_domain_S1.
    IPR006196. RNA-binding_domain_S1_IF1.
    IPR004368. TIF_IF1.
    [Graphical view]
    PfamiPF01176. eIF-1a. 1 hit.
    [Graphical view]
    SMARTiSM00316. S1. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00008. infA. 1 hit.
    PROSITEiPS50832. S1_IF1_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A3NEF8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKDDVIQMQ GEVIENLPNA TFRVKLENGH VVLGHISGKM RMHYIRILPG   50
    DKVTVELTPY DLSRARIVFR AK 72
    Length:72
    Mass (Da):8,218
    Last modified:April 3, 2007 - v1
    Checksum:i983A496214B869D9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000570 Genomic DNA. Translation: ABN84064.1.
    RefSeqiYP_001060729.1. NC_009074.1.

    Genome annotation databases

    EnsemblBacteriaiABN84064; ABN84064; BURPS668_3725.
    GeneIDi4883351.
    KEGGibpd:BURPS668_3725.
    PATRICi19253078. VBIBurPse82117_3464.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000570 Genomic DNA. Translation: ABN84064.1 .
    RefSeqi YP_001060729.1. NC_009074.1.

    3D structure databases

    ProteinModelPortali A3NEF8.
    SMRi A3NEF8. Positions 2-72.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 320373.BURPS668_3725.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABN84064 ; ABN84064 ; BURPS668_3725 .
    GeneIDi 4883351.
    KEGGi bpd:BURPS668_3725.
    PATRICi 19253078. VBIBurPse82117_3464.

    Phylogenomic databases

    eggNOGi COG0361.
    HOGENOMi HOG000221323.
    KOi K02518.
    OMAi MQGEVTE.
    OrthoDBi EOG6384SC.

    Enzyme and pathway databases

    BioCyci BPSE320373:GJ9C-3717-MONOMER.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    HAMAPi MF_00075. IF_1.
    InterProi IPR012340. NA-bd_OB-fold.
    IPR022967. RNA-binding_domain_S1.
    IPR006196. RNA-binding_domain_S1_IF1.
    IPR004368. TIF_IF1.
    [Graphical view ]
    Pfami PF01176. eIF-1a. 1 hit.
    [Graphical view ]
    SMARTi SM00316. S1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00008. infA. 1 hit.
    PROSITEi PS50832. S1_IF1_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. DeShazer D., Woods D.E., Nierman W.C.
      Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 668.

    Entry informationi

    Entry nameiIF12_BURP6
    AccessioniPrimary (citable) accession number: A3NEF8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 10, 2008
    Last sequence update: April 3, 2007
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Translation initiation factors
      List of translation initiation factor entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3