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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Actinobacillus pleuropneumoniae serotype 5b (strain L20)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaKUniRule annotation
Alternative name(s):
HSP70UniRule annotation
Heat shock 70 kDa proteinUniRule annotation
Heat shock protein 70UniRule annotation
Gene namesi
Name:dnaKUniRule annotation
Ordered Locus Names:APL_1906
OrganismiActinobacillus pleuropneumoniae serotype 5b (strain L20)
Taxonomic identifieri416269 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
Proteomesi
  • UP000001432 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000595001 – 632Chaperone protein DnaKAdd BLAST632

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei198Phosphothreonine; by autocatalysisUniRule annotation1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiA3N3K0.

Expressioni

Inductioni

By stress conditions e.g. heat shock.UniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi416269.APL_1906.

Structurei

3D structure databases

ProteinModelPortaliA3N3K0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04043.
OMAiFYSAKRF.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3N3K0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKIIGIDLG TTNSCVAVMD GDKARVIENA EGARTTPSII AYTDNETLVG
60 70 80 90 100
QPAKRQAITN PKNTLFAIKR LIGRRFESEE VQRDIKIMPF EITRADNGDA
110 120 130 140 150
WVNVKGDKLA PPQISAEVLK KMKKTAEDFL GEAVTEAVIT VPAYFNDAQR
160 170 180 190 200
QATIDAGRIA GLDVKRIINE PTAAALAFGL GSTKENQVIA VYDLGGGTFD
210 220 230 240 250
ISIIEIDNFD GEQTFEVLAT GGNTHLGGED FDNRVIDYII DEFKKEQGVD
260 270 280 290 300
LRNDPMALQR VKEAAEKAKI ELSSAQSTEV NLPYITADAT GPKHLAINVT
310 320 330 340 350
RAKLEALVED LVASSIESLK TVLKDAGKSV NEINDIILVG GQTRMPLVQQ
360 370 380 390 400
KVAEFFGKEA RKDVNPDEAV AIGAAVQGGV LKGDVKDVLL LDVTPLSLGI
410 420 430 440 450
ETMGGVMTVL IEKNTTIPTK KSQVFSTAED NQSAVTIHVL QGERKQASAN
460 470 480 490 500
KSLGQFNLEG INPAPRGMPQ IEVTFDIDAN GVINVSAKDK NTGKEQQIRI
510 520 530 540 550
QASSGLSDEE IEQMVRDAEA NAEADKKFEE LVQARNQADG IAHATRKQIE
560 570 580 590 600
EAGDALNADD KAKIEAAIAD LEKAAKGDDK AEIDAKTEAL IKASEPLMQA
610 620 630
AQAKAQAGEQ PQQSAKDDGV VDAEFEEVKD NK
Length:632
Mass (Da):67,941
Last modified:April 3, 2007 - v1
Checksum:i5F5F953A211BF11C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000569 Genomic DNA. Translation: ABN74986.1.
RefSeqiWP_005599634.1. NC_009053.1.

Genome annotation databases

EnsemblBacteriaiABN74986; ABN74986; APL_1906.
GeneIDi4848587.
KEGGiapl:APL_1906.
PATRICi20748904. VBIActPle94089_1985.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000569 Genomic DNA. Translation: ABN74986.1.
RefSeqiWP_005599634.1. NC_009053.1.

3D structure databases

ProteinModelPortaliA3N3K0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi416269.APL_1906.

Proteomic databases

PRIDEiA3N3K0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABN74986; ABN74986; APL_1906.
GeneIDi4848587.
KEGGiapl:APL_1906.
PATRICi20748904. VBIActPle94089_1985.

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04043.
OMAiFYSAKRF.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDNAK_ACTP2
AccessioniPrimary (citable) accession number: A3N3K0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: April 3, 2007
Last modified: November 2, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.