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A3N2M6 (A3N2M6_ACTP2) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
2-dehydro-3-deoxyphosphooctonate aldolase 1 HAMAP MF_00056
EC=2.5.1.55 HAMAP MF_00056
Alternative name(s):
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase 1 HAMAP MF_00056
KDO-8-phosphate synthase 1 HAMAP MF_00056
Phospho-2-dehydro-3-deoxyoctonate aldolase 1 HAMAP MF_00056
Gene names
Name:kdsA EMBL ABN74662.1
Synonyms:kdsA1 HAMAP MF_00056
Ordered Locus Names:APL_1578
OrganismActinobacillus pleuropneumoniae serotype 5b (strain L20) [Complete proteome] [HAMAP] EMBL ABN74662.1
Taxonomic identifier416269 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length286 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate. HAMAP MF_00056

Pathway

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP MF_00056

Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3. HAMAP MF_00056

Subcellular location

Cytoplasm By similarity HAMAP MF_00056.

Sequence similarities

Belongs to the KdsA family. HAMAP MF_00056

Ontologies

Keywords
   Biological processLipopolysaccharide biosynthesis HAMAP MF_00056
   Cellular componentCytoplasm HAMAP MF_00056
   Molecular functionTransferase HAMAP MF_00056 EMBL ABN74662.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processketo-3-deoxy-D-manno-octulosonic acid biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-deoxy-8-phosphooctulonate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A3N2M6 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: AA0FF8ACF7B7E448

FASTA28631,343
        10         20         30         40         50         60 
MTILNKIVKV GNIEVANDKP FTLFGGMNVL ESRDMAMRVC EQYVEVTNKL GVPYVFKASF 

        70         80         90        100        110        120 
DKANRSSIHS YRGPGMEEGL KIFQELKDTF GVSIITDVHE IYQCKPVAEV VDIIQLPAFL 

       130        140        150        160        170        180 
ARQTDLVEAM ARTGVVINVK KPQFLSPGQM GNIVEKIAEC GNENVILCDR GTNFGYDNLV 

       190        200        210        220        230        240 
VDMLGFNIMK KVSKGCPVIF DVTHSLQCRD PFGAASGGRR DQVTELARSG MAIGLAGLFL 

       250        260        270        280 
EAHPDPNSAK CDGPSALPLS KLEAFVSQMK AIDDLVKSFE EIDTSR

« Hide

References

[1]"The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b)."
Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M., Nash J.H.E.
J. Bacteriol. 190:1495-1496(2008) [PubMed: 18065534] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000569 Genomic DNA. Translation: ABN74662.1.
RefSeqYP_001054267.1. NC_009053.1.

3D structure databases

ProteinModelPortalA3N2M6.
SMRA3N2M6. Positions 5-284.
ModBaseSearch...

Protein-protein interaction databases

STRINGA3N2M6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4848960.
GenomeReviewsGene locus APL_1578 in contig CP000569_GR.
KEGGapl:APL_1578.
PATRIC20748189. VBIActPle94089_1644.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2877.
HOGENOMHBG575990.
OMAEMKHILN.
PhylomeDBA3N2M6.
ProtClustDBPRK05198.

Family and domain databases

HAMAPMF_00056. KDO8P_synth.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006269. KDO8P_synthase.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01627.
PANTHERPTHR21057:SF2. KDO8P_synthase. 1 hit.
PfamPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR01362. KDO8P_synth. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA3N2M6_ACTP2
AccessionPrimary (citable) accession number: A3N2M6
Entry history
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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