A3N2A1 (RPIA_ACTP2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase A
EC=5.3.1.6

Alternative name(s):
Phosphoriboisomerase A
Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	APL_1453

Organism

Actinobacillus pleuropneumoniae serotype 5b (strain L20) [Complete proteome] [HAMAP]

Taxonomic identifier

416269 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length	219 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 219	219	Ribose-5-phosphate isomerase A HAMAP MF_00170		PRO_1000016895

Sequences

	Sequence		Length	Mass (Da)
	A3N2A1 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: 9829E4268C4D4199	FASTA	219	23,255
	10 20 30 40 50 60 MTQQEMKKIA AQAALQFVKP DTIVGVGSGS TVNCFIDALA SMKDQIKGAV AASKASEERL 70 80 90 100 110 120 RAIGIEVFNA NEVSELDVYI DGADEITPQG AMIKGGGAAL TREKIVSSLA KKFVCIVDGS 130 140 150 160 170 180 KQVDVLGTTF PLPVEVIPMA RSYVARQLVA LGGSPEYREG VVTDNGNVIL DVHNFHIIEP 190 200 210 LKMEHTINNI AGVVTNGIFA QRYANVTIVG TPEGAKIIE

References

[1]	"The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b)." Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M., Nash J.H.E. J. Bacteriol. 190:1495-1496(2008) [PubMed: 18065534] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: L20.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000569 Genomic DNA. Translation: ABN74537.1.
RefSeq	YP_001054142.1. NC_009053.1.
3D structure databases
ProteinModelPortal	A3N2A1.
SMR	A3N2A1. Positions 1-219.
ModBase	Search...
Protein-protein interaction databases
STRING	A3N2A1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4850152.
GenomeReviews	Gene locus APL_1453 in contig CP000569_GR.
KEGG	apl:APL_1453.
PATRIC	20747893. VBIActPle94089_1512.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0120.
HOGENOM	HBG515603.
OMA	GGDPEYR.
PhylomeDB	A3N2A1.
ProtClustDB	PRK00702.
Enzyme and pathway databases
BioCyc	APLE416269:APL_1453-MONOMER.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. [Graphical view]
KO	K01807.
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. RpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_ACTP2

Accession

Primary (citable) accession number: A3N2A1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	April 3, 2007
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program