Reviewed, UniProtKB/Swiss-Prot A3N262 (MQO_ACTP2)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	APL_1414

Organism

Actinobacillus pleuropneumoniae serotype 5b (strain L20) [Complete proteome] [HAMAP]

Taxonomic identifier

416269 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length	491 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor.
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle.
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 491	491	Probable malate:quinone oxidoreductase		PRO_0000325484

Sequences

	Sequence		Length	Mass (Da)
	A3N262-1 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: CB55915CE9BDA023	FASTA	491	54,074
	10 20 30 40 50 60 MQDSSSALES YSDVTLIGAG IMSGTLGAFL TELAPEKSLA IFEKLSAVGL ESSNEWNNAG 70 80 90 100 110 120 TGHSALCELN YTEQKANGEV SVERAVKICE DFQLSLQLWS YLVETGRIQA PREFIHRIPH 130 140 150 160 170 180 ISFVQGEQNA QFLQKRYQSL AQSHLFEGMQ FSRDHQQLAQ WMPLMMQNRD SNETLAASYI 190 200 210 220 230 240 QYGTDVNFGE LTRKLFDYLV KQKAELNLNH TVKNIQRLAN GEWKLTVVDQ QGQKRVHRSK 250 260 270 280 290 300 FVFIGGGGGA LPLLQKSGIT DGKNVGGFPV SGLFMVCNNP EVIAKHNAKV YGKAKLGAPP 310 320 330 340 350 360 MSVPHLDTRF IEGKQSLLFG PFAGFTLKFL KQGSVLDLPT SVTPTNFCSV TKAGIKNLPL 370 380 390 400 410 420 AHYLMKQAML TKAQRMADLR EFVPDAKDED WDVVVAGQRV QVIKGGEMRF GTEVIRAEDG 430 440 450 460 470 480 SLAALLGASP GASTSVKAML DVLVSCFAAE LPQWQAKLTQ MLPSYGKALR NEPQLYAQIK 490 QRVDQVLALA N

References

[1]	"The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b)." Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M., Nash J.H.E. J. Bacteriol. 190:1495-1496(2008) [PubMed: 18065534] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000569 Genomic DNA. Translation: ABN74498.1.
RefSeq	YP_001054103.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4850549.
GenomeReviews	Gene locus APL_1414 in contig CP000569_GR.
KEGG	apl:APL_1414.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_ACTP2

Accession

Primary (citable) accession number: A3N262

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	April 3, 2007
Last modified:	November 4, 2008
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)