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Reviewed, UniProtKB/Swiss-Prot A3N255 (PSD_ACTP2)

Last modified February 9, 2010. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Phosphatidylserine decarboxylase proenzyme
    EC=4.1.1.65
Cleaved into the following 2 chains:
    1- Recommended name:
            Phosphatidylserine decarboxylase alpha chain
    2- Recommended name:
            Phosphatidylserine decarboxylase beta chain
Gene names
Name: psd
Ordered Locus Names: APL_1407
OrganismActinobacillus pleuropneumoniae serotype 5b (strain L20) [Complete proteome] [HAMAP]
Taxonomic identifier416269 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

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Protein attributes

Sequence length297 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

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Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 262262Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000026534
Chain263 – 29735Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000026535

Sites

Site262 – 2632Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2631Pyruvic acid (Ser) By similarity

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Sequences

Sequence LengthMass (Da)Tools
A3N255-1 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: CBD145079993FA36

FASTA29733,753
        10         20         30         40         50         60 
MSLKPYATPT YWQRVKVAFQ YIFPQLPVTR LAGWLAEQKW GAVTHFIIRT FAKQYKVNLS 

        70         80         90        100        110        120 
EAQKSNASDY ATFNEFFIRP LKENARPINQ DAQALCLPAD GKVSESGKIE DDRLLQAKGH 

       130        140        150        160        170        180 
FFTLETLLAN DQEMANKFKD GHFITTYLSP RDYHRVHMPC DATLRKMIYV PGELFSVNPF 

       190        200        210        220        230        240 
LAEHVPNLFA RNERVICEFE TEFGPMVQIL VGATITASMS TVWAGIINPP RTKEVVEYHY 

       250        260        270        280        290 
ETSGETAVHL KKGQEMGAFR LGSTVINLFP KDSVEFEAHL QAGVETRMGE RLAKIVK

« Hide

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References

[1]"The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b)."
Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M., Nash J.H.E.
J. Bacteriol. 190:1495-1496(2008) [PubMed: 18065534] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000569 Genomic DNA. Translation: ABN74491.1.
RefSeqYP_001054096.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA3N255.

Genome annotation databases

GeneID4849559.
GenomeReviewsGene locus APL_1407 in contig CP000569_GR.
KEGGapl:APL_1407.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0688.
HOGENOMHBG302256.
OMAALFSVNP.
PhylomeDBA3N255.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

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Entry information

Entry namePSD_ACTP2
AccessionPrimary (citable) accession number: A3N255
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 3, 2007
Last modified: February 9, 2010
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents