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Protein

Chaperone protein HscA homolog

Gene

hscA

Organism
Actinobacillus pleuropneumoniae serotype 5b (strain L20)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein HscA homologUniRule annotation
Gene namesi
Name:hscAUniRule annotation
Ordered Locus Names:APL_0925
OrganismiActinobacillus pleuropneumoniae serotype 5b (strain L20)
Taxonomic identifieri416269 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
Proteomesi
  • UP000001432 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000448391 – 617Chaperone protein HscA homologAdd BLAST617

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi416269.APL_0925

Structurei

3D structure databases

ProteinModelPortaliA3N0T5
SMRiA3N0T5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C9I Bacteria
COG0443 LUCA
HOGENOMiHOG000228136
KOiK04044
OMAiLRGIPAM

Family and domain databases

Gene3Di1.20.1270.10, 1 hit
2.60.34.10, 1 hit
HAMAPiMF_00679 HscA, 1 hit
InterProiView protein in InterPro
IPR018181 Heat_shock_70_CS
IPR029048 HSP70_C_sf
IPR029047 HSP70_peptide-bd_sf
IPR013126 Hsp_70_fam
IPR010236 ISC_FeS_clus_asmbl_HscA
PANTHERiPTHR19375 PTHR19375, 1 hit
PfamiView protein in Pfam
PF00012 HSP70, 1 hit
PRINTSiPR00301 HEATSHOCK70
SUPFAMiSSF100920 SSF100920, 1 hit
SSF100934 SSF100934, 1 hit
TIGRFAMsiTIGR01991 HscA, 1 hit
PROSITEiView protein in PROSITE
PS00297 HSP70_1, 1 hit
PS00329 HSP70_2, 1 hit
PS01036 HSP70_3, 1 hit

Sequencei

Sequence statusi: Complete.

A3N0T5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLQIAEPG QTAAPHQHRL AVGIDLGTTN SLVASVRSGQ TQVLLDDQER
60 70 80 90 100
ALVPSVVHYG EQQKTVGIEA FAQASLDPQN TVISAKRLIG RSLADVQTRY
110 120 130 140 150
PDLPYQFIAS DNGLPLIQTK QGNKSPVEVS ADILSHLNRF AEQRLGGELS
160 170 180 190 200
GVVITVPAYF DDAQRQSTKD AARLAGLNVL RLLNEPTAAA IAYGLDSGQE
210 220 230 240 250
GVIAVYDLGG GTFDISILRL SRGVFEVLAT GGDTALGGDD FDHLLADWIA
260 270 280 290 300
QQANYQPQNA NEQRELLTLA TQTKVALSQA VETEVKFANW QGTVSREQFN
310 320 330 340 350
ELIQLLVKRS LMTCRRALKD AGVEGEEIRE VVMVGGSTRV PFVREQVGEF
360 370 380 390 400
FGKQPLTSID PDKVVALGAA IQADILVGNK PDSEMLLLDV VPLSLGIETM
410 420 430 440 450
GGLVEKIIPR NMTIPVARAQ EFTTAKDGQT AMSVHVLQGE RELVEDCRSL
460 470 480 490 500
GRFTLRGIPP MVAGAATIRV TYQVDADGLL SVTAMEKSTK VQASIQIKPS
510 520 530 540 550
YGLTDEEVTQ MIKSSMTNAK EDMEARQLAE QRVEADRTID TVISALQQDG
560 570 580 590 600
AEVLSVEEFK LIEAEIAKLI QLKQGTDRQA IAQGVKDLDL ATQTFAAKRM
610
NLSIQKALAG KAVDEII
Length:617
Mass (Da):66,704
Last modified:April 3, 2007 - v1
Checksum:iBEDEA547965946DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000569 Genomic DNA Translation: ABN74021.1
RefSeqiWP_009874858.1, NC_009053.1

Genome annotation databases

EnsemblBacteriaiABN74021; ABN74021; APL_0925
GeneIDi4849751
KEGGiapl:APL_0925

Similar proteinsi

Entry informationi

Entry nameiHSCA_ACTP2
AccessioniPrimary (citable) accession number: A3N0T5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 3, 2007
Last modified: February 28, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health