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A3N0B0 (AROC_ACTP2) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:APL_0748
OrganismActinobacillus pleuropneumoniae serotype 5b (strain L20) [Complete proteome] [HAMAP]
Taxonomic identifier416269 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length360 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 360360Chorismate synthase HAMAP MF_00300
PRO_1000022456

Sequences

Sequence LengthMass (Da)Tools
A3N0B0 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: 656C2693F5FB8106

FASTA36038,893
        10         20         30         40         50         60 
MAGNSIGQLF KVTTFGESHG IALGCIVDGV PPNMALSEAD IQPDLDRRKP GTSRYTTPRR 

        70         80         90        100        110        120 
EDDEVQILSG VFEGKTTGTS IGLIIKNADQ RSKDYGDIAD KFRPGHADYT YQQKYGIRDY 

       130        140        150        160        170        180 
RGGGRSSARE TAMRVAAGAI AKKYLREQFG IEVRGYLSQI GNVKINPETV ADISKIDWQQ 

       190        200        210        220        230        240 
VASNPFFCPD PVAVEGFGEL IRELKKDGDS IGAKLTVVAE NVPVGLGEPV FDRLDADLAH 

       250        260        270        280        290        300 
ALMSINAVKA VEIGDGFDVV EQRGSEHRDE MTPQGFVSNH AGGILGGISS GQPIIAHIAL 

       310        320        330        340        350        360 
KPTSSIMVPG RSVNLNNEQV ELITKGRHDP CVGIRAVPIA EAMTAIILLD HLLRFKAQCR

« Hide

References

[1]"The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b)."
Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M., Nash J.H.E.
J. Bacteriol. 190:1495-1496(2008) [PubMed: 18065534] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: L20.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000569 Genomic DNA. Translation: ABN73846.1.
RefSeqYP_001053451.1. NC_009053.1.

3D structure databases

ProteinModelPortalA3N0B0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA3N0B0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4848838.
GenomeReviewsGene locus APL_0748 in contig CP000569_GR.
KEGGapl:APL_0748.
PATRIC20746366. VBIActPle94089_0783.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0082.
HOGENOMHBG292336.
OMASRFTTQR.
PhylomeDBA3N0B0.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycAPLE416269:APL_0748-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_ACTP2
AccessionPrimary (citable) accession number: A3N0B0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 3, 2007
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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