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A3MZ57 (CAPP_ACTP2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:APL_0339
OrganismActinobacillus pleuropneumoniae serotype 5b (strain L20) [Complete proteome] [HAMAP]
Taxonomic identifier416269 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus

Protein attributes

Sequence length879 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 879879Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_1000025543

Sites

Active site1381 By similarity
Active site5451 By similarity

Sequences

Sequence LengthMass (Da)Tools
A3MZ57 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: 4311EE8513C0894A

FASTA87999,144
        10         20         30         40         50         60 
MNQPYSAMRN NIHMLGDFLG ETIREAQGNE ILELIESIRV LSRDSRAGDE KAREQLLDKL 

        70         80         90        100        110        120 
ANISTENVLP VARAFSQFLN LTNIAEQYQT ISRHHQDESL GNRSLSALFA RLKAQGTPVE 

       130        140        150        160        170        180 
TVIKTVEKLS IELVLTAHPT EVTRRSLVHK HVEINKCLGQ LEHDDLTEAE QTKLKRRLMQ 

       190        200        210        220        230        240 
LIALAWHTNE IRAARPTPVD EAKWGMAIIE NSLWKAVPDF CRELNFQLEK HFDVQYEVAL 

       250        260        270        280        290        300 
SPVRFSSWMG GDRDGNPFVT AEITQKVLRM NRWKAAELFL NDVSDLVEEL SIVQCTPEFR 

       310        320        330        340        350        360 
EKYGDHIEPY RVVVKGLRSK LQKTLTYFGE LIEAKPTTVD PSEIITCDND LWEPLYDCYQ 

       370        380        390        400        410        420 
SLHACGMRII ANGSLLDCLR RIRCFGLGLS RLDIRQESSR HETAIAEITR YIGLGDYAQW 

       430        440        450        460        470        480 
TEDDKQAFLV RELSSRRPLV PTNWTPSPET QEILDTCKVV AQQPEGTISA YVISMAREAS 

       490        500        510        520        530        540 
DVLAVHLLLK EAGCNYTLPV APLFETLDDL DHSEKVMTDL FNIGWYRGVI NNYQMVMIGY 

       550        560        570        580        590        600 
SDSAKDAGML AASWAQYRAQ EALVNLAEKY HIELVLFHGR GGTVGRGGAP AHAALLSQPP 

       610        620        630        640        650        660 
RSLKSGLRVT EQGEMIRFKL GLPAVAVETL NLYASAILEA NLLPPPEPKQ KWRDIMDKGA 

       670        680        690        700        710        720 
AISCEIYRGV VRGEPDFVPY FRSATPEQEL GKLPLGSRPS KRNPNGGVES LRAIPWIFAW 

       730        740        750        760        770        780 
MQNRLMLPAW LGAGAALRQM IEQGEESTLK EMCNEWPFFS TRIGMLEMVF SKADLWLAEH 

       790        800        810        820        830        840 
YDQRLVAKEL HRLGKTLRAQ LSADIQTVLT LAHDGQLMAD LPWIAESIAL RNVYTDPLNL 

       850        860        870 
LQVELLQRLR SQGEVRDPQL EQALMITITG IAAGMRNTG 

« Hide

References

[1]"The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b)."
Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M., Nash J.H.E.
J. Bacteriol. 190:1495-1496(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: L20.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000569 Genomic DNA. Translation: ABN73443.1.
RefSeqYP_001053048.1. NC_009053.1.

3D structure databases

ProteinModelPortalA3MZ57.
SMRA3MZ57. Positions 5-879.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING416269.APL_0339.

Proteomic databases

PRIDEA3MZ57.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABN73443; ABN73443; APL_0339.
GeneID4848495.
KEGGapl:APL_0339.
PATRIC20745490. VBIActPle94089_0348.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238648.
KOK01595.
OMAISCQHYR.
OrthoDBEOG6TJ7T8.

Enzyme and pathway databases

BioCycAPLE416269:GHV7-348-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_ACTP2
AccessionPrimary (citable) accession number: A3MZ57
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 3, 2007
Last modified: May 14, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families