Reviewed, UniProtKB/Swiss-Prot A3MZ45 (SELD_ACTP2)

Names and origin

Protein names

Recommended name:
    Selenide, water dikinase
    EC=2.7.9.3
Alternative name(s):
    Selenophosphate synthetase
    Selenium donor protein

Gene names

Name:	selD
Ordered Locus Names:	APL_0327

Organism

Actinobacillus pleuropneumoniae serotype 5b (strain L20) [Complete proteome] [HAMAP]

Taxonomic identifier

416269 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length	347 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes selenophosphate from selenide and ATP By similarity. HAMAP MF_00625
Catalytic activity	ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625
Cofactor	Magnesium By similarity. HAMAP MF_00625
Sequence similarities	Belongs to the selenophosphate synthetase 1 family. Class I subfamily.
Sequence caution	The sequence ABN73431.1 differs from that shown. Reason: Erroneous termination at position 17. Translated as Sec.

Ontologies

Keywords
Coding sequence diversity	Selenocysteine
Ligand	ATP-binding Magnesium Nucleotide-binding Selenium
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP selenide, water dikinase activity Inferred from electronic annotation. Source: HAMAP selenium binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 347	347	Selenide, water dikinase HAMAP MF_00625		PRO_0000318662
Regions
	Nucleotide binding	230 – 236	7	ATP Potential
Sites
	Active site	17	1	Potential
	Site	20	1	Important for catalytic activity By similarity
Amino acid modifications
	Non-standard residue	17	1	Selenocysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	A3MZ45-1 [UniParc]. Last modified February 26, 2008. Version 2. Checksum: 03FB22A71E979310	FASTA	347	36,603
	10 20 30 40 50 60 MAEEPIRLTQ YSHGAGUGCK ISPKVLGTIL QSQLDKFIDP NLLVGNETAD DAAVYDIGNG 70 80 90 100 110 120 IGIISTTDFF MPIVDDPFDF GRIAAANALS DVFAMGGKPI MAIAILGFPV NKLPAEVAQK 130 140 150 160 170 180 IVEGGRFACQ QAGIALAGGH SIDSPEPIFG LAVTGTVSTE QVKKNASAQA GCELFLTKPL 190 200 210 220 230 240 GIGVLTTAEK KGLLKVEHQN LARDVMCQIN LIGAQFSQLA DVTAMTDVTG FGLLGHLSEI 250 260 270 280 290 300 CQGSNVRAEV NSAEIHTLDG VKDYIAQGAV PGGTNRNFDS YGHLISAMSD EQKAILCDPQ 310 320 330 340 TSGGLLIAVR PQAVEKVQQI AKQANIPLFR VGRLLEADTM KPLIEVI

References

[1]	"The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b)." Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M., Nash J.H.E. J. Bacteriol. 190:1495-1496(2008) [PubMed: 18065534] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000569 Genomic DNA. Translation: ABN73431.1. Sequence problems.
RefSeq	YP_001053036.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A3MZ45.
Genome annotation databases
GeneID	4850157.
GenomeReviews	Gene locus APL_0327 in contig CP000569_GR.
KEGG	apl:APL_0327.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0709.
HOGENOM	HBG383791.
Family and domain databases
HAMAP	MF_00625. SelD. [Tree]
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR016188. PurM_N-like. IPR004536. SelD. [Graphical view]
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
PIRSF	PIRSF036407. Selenphspht_syn. 1 hit.
TIGRFAMs	TIGR00476. selD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SELD_ACTP2

Accession

Primary (citable) accession number: A3MZ45

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	February 26, 2008
Last modified:	February 9, 2010
This is version 17 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)