Reviewed,
UniProtKB/Swiss-Prot A3MYW5 (ARGB_ACTP2)
Last modified
February 9, 2010.
Version 27.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Acetylglutamate kinase EC=2.7.2.8 Alternative name(s): NAG kinase Short name=AGK N-acetyl-L-glutamate 5-phosphotransferase | ||||
| Gene names |
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| Organism | Actinobacillus pleuropneumoniae serotype 5b (strain L20) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 416269 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus |
Protein attributes
| Sequence length | 284 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082 |
| Pathway | Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082 |
| Subcellular location | Cytoplasm Probable HAMAP MF_00082. |
| Sequence similarities | Belongs to the acetylglutamate kinase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Arginine biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | arginine biosynthetic process Inferred from electronic annotation. Source: HAMAP proline biosynthetic processInferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: HAMAP acetylglutamate kinase activityInferred from electronic annotation. Source: HAMAP glutamate 5-kinase activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 284 | 284 | Acetylglutamate kinase HAMAP MF_00082 | PRO_0000335605 | |||||
Regions | |||||||||
| Region | 66 – 67 | 2 | Substrate binding By similarity | ||||||
Sites | |||||||||
| Binding site | 88 | 1 | Substrate By similarity | ||||||
| Binding site | 179 | 1 | Substrate By similarity | ||||||
| Site | 31 | 1 | Transition state stabilizer By similarity | ||||||
| Site | 242 | 1 | Transition state stabilizer By similarity | ||||||
Sequences
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References
| [1] | "The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b)." Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M., Nash J.H.E. J. Bacteriol. 190:1495-1496(2008) [PubMed: 18065534] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000569 Genomic DNA. Translation: ABN73351.1. |
| RefSeq | YP_001052956.1. |
3D structure databases | |
| SMR | A3MYW5. Positions 7-283. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A3MYW5. |
Genome annotation databases | |
| GeneID | 4850320. |
| GenomeReviews | Gene locus APL_0243 in contig CP000569_GR. |
| KEGG | apl:APL_0243. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0548. |
| HOGENOM | HBG497643. |
| OMA | MDIVEMV. |
| PhylomeDB | A3MYW5. |
Family and domain databases | |
| HAMAP | MF_00082_B. ArgB_B. [Tree] |
| InterPro | IPR004662. AcgluKinase. IPR001048. Asp/Glu/Uridylate_kinase. IPR011148. GlcNAc_kinase. IPR001057. Glu_5kinase. [Graphical view] |
| Gene3D | G3DSA:3.40.1160.10. Aa_kinase. 1 hit. |
| Pfam | PF00696. AA_kinase. 1 hit. [Graphical view] |
| PIRSF | PIRSF000728. NAGK. 1 hit. |
| PRINTS | PR00474. GLU5KINASE. |
| TIGRFAMs | TIGR00761. argB. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | ARGB_ACTP2 | ||||||||
| Accession | Primary (citable) accession number: A3MYW5 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


