Reviewed, UniProtKB/Swiss-Prot A3MYL5 (ACYP_ACTP2)

Names and origin

Protein names

Recommended name:
    Acylphosphatase
    EC=3.6.1.7
Alternative name(s):
    Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	APL_0143

Organism

Actinobacillus pleuropneumoniae serotype 5b (strain L20) [Complete proteome] [HAMAP]

Taxonomic identifier

416269 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length	90 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 90	90	Acylphosphatase HAMAP MF_01450		PRO_0000326642
Regions
	Domain	3 – 90	88	Acylphosphatase-like
Sites
	Active site	18	1	By similarity
	Active site	36	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A3MYL5-1 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: B4429D7F001F975C	FASTA	90	10,133
	10 20 30 40 50 60 MQQKLFIVTG HVQSVGFRFF TLQEAGKIGI KGYVKNRPEG SVEVVAVGSD AQMAAFRNWL 70 80 90 QKGPPTSVVC NLIEQSYQGS EQFEHFEIRR

References

[1]	"The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b)." Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M., Nash J.H.E. J. Bacteriol. 190:1495-1496(2008) [PubMed: 18065534] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000569 Genomic DNA. Translation: ABN73251.1.
RefSeq	YP_001052856.1.
3D structure databases
SMR	A3MYL5. Positions 1-88.
ModBase	Search...
Protein-protein interaction databases
STRING	A3MYL5.
Genome annotation databases
GeneID	4849368.
GenomeReviews	Gene locus APL_0143 in contig CP000569_GR.
KEGG	apl:APL_0143.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1254.
HOGENOM	HBG750266.
OMA	TGYARNQ.
PhylomeDB	A3MYL5.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
PANTHER	PTHR10029. Acylphosphatase. 1 hit.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
PROSITE	PS00150. ACYLPHOSPHATASE_1. False negative. PS00151. ACYLPHOSPHATASE_2. 1 hit. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_ACTP2

Accession

Primary (citable) accession number: A3MYL5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	April 3, 2007
Last modified:	January 19, 2010
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)