Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A3MY79

- LPXB_ACTP2

UniProt

A3MY79 - LPXB_ACTP2

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Actinobacillus pleuropneumoniae serotype 5b (strain L20)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (03 Apr 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

    Catalytic activityi

    UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. lipid A biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

    Enzyme and pathway databases

    BioCyciAPLE416269:GHV7-7-MONOMER.
    UniPathwayiUPA00359; UER00481.

    Protein family/group databases

    CAZyiGT19. Glycosyltransferase Family 19.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
    Gene namesi
    Name:lpxBUniRule annotation
    Ordered Locus Names:APL_0007
    OrganismiActinobacillus pleuropneumoniae serotype 5b (strain L20)
    Taxonomic identifieri416269 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
    ProteomesiUP000001432: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 393393Lipid-A-disaccharide synthasePRO_1000049381Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi416269.APL_0007.

    Structurei

    3D structure databases

    ProteinModelPortaliA3MY79.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LpxB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0763.
    HOGENOMiHOG000018003.
    KOiK00748.
    OMAiVSPITYR.
    OrthoDBiEOG6FBWZR.

    Family and domain databases

    HAMAPiMF_00392. LpxB.
    InterProiIPR003835. Glyco_trans_19.
    [Graphical view]
    PfamiPF02684. LpxB. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00215. lpxB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A3MY79-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMTKEAPLIA LVAGEISGDI LGAGLINALK LHYPNARFIG VAGPRMIQAG    50
    CETLFDMEEL AVMGLAEVVK HLPRLLKRRK QVIETMLAEK PDIFIGIDAP 100
    DFNLTVEEKL KASGIKTIHY VSPSVWAWRQ NRVHKIARAT NLVLAFLPFE 150
    KAFYDRFNVP CRFIGHTMAD TIALKPNRAE ACVGLNLDEA QRYLAILVGS 200
    RASEVGFLAE PFLKAAQILK QQYPDLQFLV PLVNDKRIAQ FEQIKAQVAP 250
    ELSVHILKGN ARQAMIAAEA SLLASGTAAL EGMLCKSPMV VGYKMKAMTY 300
    WLAKRLVKTK YISLPNLLAD EMLVPELIQD ECNPENLAWY LGNYLADDAD 350
    HRKQRNELKQ RFTELHKLIQ CDADAQAAQA VVDVLEANTS DQN 393
    Length:393
    Mass (Da):43,749
    Last modified:April 3, 2007 - v1
    Checksum:i1975B14EBD68282E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000569 Genomic DNA. Translation: ABN73115.1.
    RefSeqiWP_009874745.1. NC_009053.1.
    YP_001052720.1. NC_009053.1.

    Genome annotation databases

    EnsemblBacteriaiABN73115; ABN73115; APL_0007.
    GeneIDi4850465.
    KEGGiapl:APL_0007.
    PATRICi20744788. VBIActPle94089_0008.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000569 Genomic DNA. Translation: ABN73115.1 .
    RefSeqi WP_009874745.1. NC_009053.1.
    YP_001052720.1. NC_009053.1.

    3D structure databases

    ProteinModelPortali A3MY79.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 416269.APL_0007.

    Protein family/group databases

    CAZyi GT19. Glycosyltransferase Family 19.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABN73115 ; ABN73115 ; APL_0007 .
    GeneIDi 4850465.
    KEGGi apl:APL_0007.
    PATRICi 20744788. VBIActPle94089_0008.

    Phylogenomic databases

    eggNOGi COG0763.
    HOGENOMi HOG000018003.
    KOi K00748.
    OMAi VSPITYR.
    OrthoDBi EOG6FBWZR.

    Enzyme and pathway databases

    UniPathwayi UPA00359 ; UER00481 .
    BioCyci APLE416269:GHV7-7-MONOMER.

    Family and domain databases

    HAMAPi MF_00392. LpxB.
    InterProi IPR003835. Glyco_trans_19.
    [Graphical view ]
    Pfami PF02684. LpxB. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00215. lpxB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b)."
      Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M., Nash J.H.E.
      J. Bacteriol. 190:1495-1496(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: L20.

    Entry informationi

    Entry nameiLPXB_ACTP2
    AccessioniPrimary (citable) accession number: A3MY79
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: April 3, 2007
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3