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A3MV95

- SYE_PYRCJ

UniProt

A3MV95 - SYE_PYRCJ

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Protein

Glutamate--tRNA ligase

Gene

gltX

Organism
Pyrobaculum calidifontis (strain JCM 11548 / VA1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).UniRule annotation

Catalytic activityi

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glutamate-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPCAL410359:GIX2-1166-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate--tRNA ligaseUniRule annotation (EC:6.1.1.17UniRule annotation)
Alternative name(s):
Glutamyl-tRNA synthetaseUniRule annotation
Short name:
GluRSUniRule annotation
Gene namesi
Name:gltXUniRule annotation
Ordered Locus Names:Pcal_1137
OrganismiPyrobaculum calidifontis (strain JCM 11548 / VA1)
Taxonomic identifieri410359 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
ProteomesiUP000001431: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 570570Glutamate--tRNA ligasePRO_1000057200Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi410359.Pcal_1137.

Structurei

3D structure databases

ProteinModelPortaliA3MV95.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi107 – 11711"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000073585.
KOiK01885.
OMAiAFRIIDT.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00022_A. Glu_tRNA_synth_A.
InterProiIPR004526. Glu-tRNA-synth_arc/euk.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR022888. Glu_tRNA_synth_arc.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00463. gltX_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

A3MV95-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNIEEVALKY ALANAVKYGG KADVKAVMAK IMAEVPELRP RAREVKEVVE
60 70 80 90 100
AVVARVNAMS LEEQRRLLEE KWPEALEEKR PEQKRPGIEA LPDLPKVKGG
110 120 130 140 150
VVVRFAPNPD FVLHLGSARP AILNYAYRLK YGGRFILRFE DTDPRTKRPL
160 170 180 190 200
VTEEVNAYEA IREDLRWLGV SWDEEYIQSR RMEVYYDYAK RLLAMGAAYV
210 220 230 240 250
DLCRPEEWRR LRNEGRACPH RSQSPEENLE LWDKMLEGRF REGEAVVRIK
260 270 280 290 300
TDLSHPDPSV RDWVAFRIID TSKTPHPLVG DKYIVWPTYN FAVSIDDHLM
310 320 330 340 350
GVTHVLRAQE HSVNTVKQSY VFKHFGWEQP VTIHFGRLKI EGATLSKSKL
360 370 380 390 400
KALKVRYDDP TLPTLAGLRA RGILPEAIWE LILTVGIKPS DSTVALSNLF
410 420 430 440 450
ALNRKKIEPV ANRYMYVADP VRLVFEADRE LVAKVPYHPS FRERGERVYR
460 470 480 490 500
LGPGRVEVFV QRQDVKEGAV VRLMELANVE IERVEGGVAY GRLHSLSLEE
510 520 530 540 550
ARKIGAPIIQ WVVDPVEVRV VRPWAPGRKV EEVGLGEAVL RGVEVGAYAQ
560 570
FFRYGFVKKI GPDVFIYVHD
Length:570
Mass (Da):65,246
Last modified:April 3, 2007 - v1
Checksum:iC2C817CE798CA6C8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000561 Genomic DNA. Translation: ABO08562.1.
RefSeqiWP_011849820.1. NC_009073.1.
YP_001056028.1. NC_009073.1.

Genome annotation databases

EnsemblBacteriaiABO08562; ABO08562; Pcal_1137.
GeneIDi4908841.
KEGGipcl:Pcal_1137.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000561 Genomic DNA. Translation: ABO08562.1 .
RefSeqi WP_011849820.1. NC_009073.1.
YP_001056028.1. NC_009073.1.

3D structure databases

ProteinModelPortali A3MV95.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 410359.Pcal_1137.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABO08562 ; ABO08562 ; Pcal_1137 .
GeneIDi 4908841.
KEGGi pcl:Pcal_1137.

Phylogenomic databases

eggNOGi COG0008.
HOGENOMi HOG000073585.
KOi K01885.
OMAi AFRIIDT.

Enzyme and pathway databases

BioCyci PCAL410359:GIX2-1166-MONOMER.

Family and domain databases

Gene3Di 1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPi MF_00022_A. Glu_tRNA_synth_A.
InterProi IPR004526. Glu-tRNA-synth_arc/euk.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR022888. Glu_tRNA_synth_arc.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR10119. PTHR10119. 1 hit.
Pfami PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view ]
PRINTSi PR00987. TRNASYNTHGLU.
SUPFAMi SSF50715. SSF50715. 1 hit.
TIGRFAMsi TIGR00463. gltX_arch. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JCM 11548 / VA1.

Entry informationi

Entry nameiSYE_PYRCJ
AccessioniPrimary (citable) accession number: A3MV95
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: April 3, 2007
Last modified: October 29, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3