Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A3MTU7

- IF2P_PYRCJ

UniProt

A3MTU7 - IF2P_PYRCJ

Protein

Probable translation initiation factor IF-2

Gene

infB

Organism
Pyrobaculum calidifontis (strain JCM 11548 / VA1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (03 Apr 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi14 – 218GTPUniRule annotation
    Nucleotide bindingi80 – 845GTPUniRule annotation
    Nucleotide bindingi134 – 1374GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: UniProtKB-HAMAP
    2. GTP binding Source: UniProtKB-KW
    3. translation initiation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciPCAL410359:GIX2-656-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable translation initiation factor IF-2UniRule annotation
    Gene namesi
    Name:infBUniRule annotation
    Ordered Locus Names:Pcal_0638
    OrganismiPyrobaculum calidifontis (strain JCM 11548 / VA1)
    Taxonomic identifieri410359 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
    ProteomesiUP000001431: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. intracellular Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 592592Probable translation initiation factor IF-2PRO_0000335533Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi410359.Pcal_0638.

    Structurei

    3D structure databases

    ProteinModelPortaliA3MTU7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini5 – 226222tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni14 – 218G1By similarity
    Regioni39 – 435G2By similarity
    Regioni80 – 834G3By similarity
    Regioni134 – 1374G4By similarity
    Regioni202 – 2043G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0532.
    HOGENOMiHOG000105770.
    KOiK03243.
    OMAiIVCVMGH.

    Family and domain databases

    Gene3Di3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_00100_A. IF_2_A.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR029459. EFTU-type.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR004544. TIF_aIF-2_arc.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF14578. GTP_EFTU_D4. 1 hit.
    PF11987. IF-2. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00491. aIF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS51722. G_TR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A3MTU7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQQKIRSPFV VVMGHVDVGK TLLLDKIRGT SVAYREPGMI TQHIGMSLVP    50
    WPAVEKFAGP LVDRLKLRGR IWIPGFLFID TPGHAAFSNL RKRGGSVADL 100
    AILVVDITSG LEDQGVESLK LIQSRGVPFV IAANKLDRIY GWKSVENRPF 150
    LFAVEEQEWH AVATLEEQIG KLITQLANLG IDADRYDRVR DFSKQVPIVP 200
    TSAVTGEGVA DLLLVLAGVS QRFIPREKLQ VRDGPARGVV MEVKEERGLG 250
    VVADVILYDG KLRKGDVIVT AGLDGSRQAK VRMLIMPKSL EEMRDPEDKF 300
    MAVQEVEAAA GVRVVAEGLE GVVAGAPLLA VWDPKDLPEA LKSVGEEIAE 350
    IKIESDKEGV IVRADTFGTL ESIILFLRQQ GVPVRKADVG PPTHKDVVEA 400
    VLSRRKNPAY GAILAFNVKV PPEVETEAQS SGVKIIRGEI LYRIFDEYVK 450
    WSTEVKTKTV EQVLSQLTRP AKIQILPGYV FRRSDPAIVG VKVLAGTLKP 500
    GVTLAKDGRE VGKVMQIQRQ GKPVAEAVAG DEVAISIQGD VIVGRQIKEG 550
    DVLYVYIPDE QARQWLFRYK QYLRKDEVEA LEEYLKTRKK SA 592
    Length:592
    Mass (Da):65,291
    Last modified:April 3, 2007 - v1
    Checksum:i5B7A4F3545646AD1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000561 Genomic DNA. Translation: ABO08064.1.
    RefSeqiYP_001055530.1. NC_009073.1.

    Genome annotation databases

    EnsemblBacteriaiABO08064; ABO08064; Pcal_0638.
    GeneIDi4908230.
    KEGGipcl:Pcal_0638.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000561 Genomic DNA. Translation: ABO08064.1 .
    RefSeqi YP_001055530.1. NC_009073.1.

    3D structure databases

    ProteinModelPortali A3MTU7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 410359.Pcal_0638.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABO08064 ; ABO08064 ; Pcal_0638 .
    GeneIDi 4908230.
    KEGGi pcl:Pcal_0638.

    Phylogenomic databases

    eggNOGi COG0532.
    HOGENOMi HOG000105770.
    KOi K03243.
    OMAi IVCVMGH.

    Enzyme and pathway databases

    BioCyci PCAL410359:GIX2-656-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_00100_A. IF_2_A.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR029459. EFTU-type.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR004544. TIF_aIF-2_arc.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF14578. GTP_EFTU_D4. 1 hit.
    PF11987. IF-2. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00491. aIF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS51722. G_TR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JCM 11548 / VA1.

    Entry informationi

    Entry nameiIF2P_PYRCJ
    AccessioniPrimary (citable) accession number: A3MTU7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: April 3, 2007
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3