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A3MSH1 (A3MSH1_PYRCJ) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Ordered Locus Names:Pcal_0150 EMBL ABO07588.1
OrganismPyrobaculum calidifontis (strain JCM 11548 / VA1) [Complete proteome] [HAMAP] EMBL ABO07588.1
Taxonomic identifier410359 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum

Protein attributes

Sequence length334 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the FPP/GGPP synthase family. RuleBase RU004466

Ontologies

Keywords
   Biological processIsoprene biosynthesis RuleBase RU004466
   LigandChloride PDB 4DHD PDB 4GP1
   Molecular functionTransferase RuleBase RU004466
   Technical term3D-structure PDB 4DHD PDB 4GP1 PDB 4GP2
Complete proteome
Gene Ontology (GO)
   Biological_processisoprenoid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functiontransferase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region62 – 632Chloride binding PDB 4DHD PDB 4GP1

Sites

Binding site441Phosphate
Binding site761Phosphate
Binding site791Acetate
Binding site831Acetate
Binding site931Phosphate

Sequences

Sequence LengthMass (Da)Tools
A3MSH1 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: EA143E3BBA183661

FASTA33437,046
        10         20         30         40         50         60 
MDVVSRLHQK YGAEVEKALV RYLSIGLAED FREAVLYQVK TGGKRLRPLL TLAAAEAVSG 

        70         80         90        100        110        120 
QWRPALPAAA IVELIHNYSL IYDDIIDRGD VRRGLPTVRK AFGDNAAILV GIWYREAIEE 

       130        140        150        160        170        180 
AVLDTPKPTL FAKEVAEVIK AIDEGERLDI LFEAAGRSDP YFVQARWREV TLDDYIKMVS 

       190        200        210        220        230        240 
LKTGALIAAA AKWGVLSVSD DRGLAEAAWN FGMAAGVAFQ IIDDVLDIYG DPKKFGKEIG 

       250        260        270        280        290        300 
KDIKEHKRGN AVVAVALSHL GEGERRRLLE ILAREVVEEA DVREAVALLD SVGAREEALR 

       310        320        330 
LAARYREEAE RHLAKIPNNG TLKELLDFIV AREY 

« Hide

References

« Hide 'large scale' references
[1]"Complete sequence of Pyrobaculum calidifontis JCM 11548."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Cozen A.E., Fitz-Gibbon S.T., House C.H., Saltikov C., Lowe T.M., Richardson P.
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JCM 11548 / VA1.
[2]"Crystal Structure of Isoprenoid Synthase from Pyrobaculum Calidifontis."
Patskovsky Y., Toro R., Bhosle R., Hillerich B., Seidel R.D., Washington E., Scott Glenn A., Chowdury S., Evans B., Hammonds J., Zencheck W.D., Imker H.J., Poulter C.D., Gerlt J.A., Almo S.C.
Submitted (AUG-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS).
[3]"Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily."
Wallrapp F.H., Pan J.J., Ramamoorthy G., Almonacid D.E., Hillerich B.S., Seidel R., Patskovsky Y., Babbitt P.C., Almo S.C., Jacobson M.P., Poulter C.D.
Proc. Natl. Acad. Sci. U.S.A. 110:E1196-E1202(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS) IN COMPLEX WITH ACETATE; CHLORIDE AND PHOSPHATE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000561 Genomic DNA. Translation: ABO07588.1.
RefSeqYP_001055054.1. NC_009073.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4DHDX-ray1.65A1-334[»]
4GP1X-ray1.94A1-334[»]
4GP2X-ray2.00A/B1-334[»]
ProteinModelPortalA3MSH1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING410359.Pcal_0150.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABO07588; ABO07588; Pcal_0150.
GeneID4909904.
KEGGpcl:Pcal_0150.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0142.
HOGENOMHOG000009101.
KOK13787.
OMAAKWGVLS.

Enzyme and pathway databases

BioCycPCAL410359:GIX2-152-MONOMER.

Family and domain databases

Gene3D1.10.600.10. 1 hit.
InterProIPR000092. Polyprenyl_synt.
IPR017446. Polyprenyl_synth-rel.
IPR008949. Terpenoid_synth.
[Graphical view]
PANTHERPTHR12001. PTHR12001. 1 hit.
PfamPF00348. polyprenyl_synt. 1 hit.
[Graphical view]
SUPFAMSSF48576. SSF48576. 1 hit.
PROSITEPS00723. POLYPRENYL_SYNTHASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA3MSH1_PYRCJ
AccessionPrimary (citable) accession number: A3MSH1
Entry history
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: May 14, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)