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A3MLY6 (A3MLY6_BURM7) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Succinylglutamate desuccinylase HAMAP-Rule MF_00767

EC=3.5.1.96 HAMAP-Rule MF_00767
Gene names
Name:astE HAMAP-Rule MF_00767 EMBL ABO06240.1
Ordered Locus Names:BMA10247_1731 EMBL ABO06240.1
OrganismBurkholderia mallei (strain NCTC 10247) [Complete proteome] [HAMAP] EMBL ABO06240.1
Taxonomic identifier320389 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length349 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transforms N(2)-succinylglutamate into succinate and glutamate By similarity. HAMAP-Rule MF_00767 SAAS SAAS016681

Catalytic activity

N-succinyl-L-glutamate + H2O = succinate + L-glutamate. HAMAP-Rule MF_00767 SAAS SAAS016681

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00767 SAAS SAAS016681

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 5/5. HAMAP-Rule MF_00767 SAAS SAAS016681

Sequence similarities

Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. HAMAP-Rule MF_00767

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2291 By similarity HAMAP-Rule MF_00767
Metal binding701Zinc By similarity HAMAP-Rule MF_00767
Metal binding731Zinc By similarity HAMAP-Rule MF_00767
Metal binding1661Zinc By similarity HAMAP-Rule MF_00767

Sequences

Sequence LengthMass (Da)Tools
A3MLY6 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: 1D1F32BB7F0A1AF3

FASTA34937,622
        10         20         30         40         50         60 
MTSSADSGRD AAWLDDFLAL TLAGDAPPAE AGECAARAVR WRWLGDGLLR LEPADAAQRM 

        70         80         90        100        110        120 
QSVLVSAGVH GDETAPIELL STLVRDIARG ALPLRCRLLV ALGNPGAMRA GERYLDDDLN 

       130        140        150        160        170        180 
RLFGGRHAQL AASREAPRAA QLEAAAALFF STAGRARGAR WHIDMHTAIR TSVFEQFALL 

       190        200        210        220        230        240 
PHTGEPPTRT MFEWLGEAQI AAVLLHTTKG STFSHFTAQA CGALACTLEL GKVMPFGAND 

       250        260        270        280        290        300 
LSRFAPADAA VRRLVSGRRD APRGALPRAF TVVDQITKQS DALELFVAND VPNFTPFARG 

       310        320        330        340 
TLLARDGDYR YAVRHEQERI VFPNPSVKPG LRAGLLVIET TRDTHAALA 

« Hide

References

[1]DeShazer D., Woods D.E., Nierman W.C.
Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCTC 10247 EMBL ABO06240.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000548 Genomic DNA. Translation: ABO06240.1.
RefSeqYP_001081272.1. NC_009080.1.

3D structure databases

ProteinModelPortalA3MLY6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING320389.BMA10247_1731.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABO06240; ABO06240; BMA10247_1731.
GeneID4891618.
KEGGbmn:BMA10247_1731.
PATRIC19145858. VBIBurMal96640_3975.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2988.
HOGENOMHOG000280300.
KOK05526.
OMADHAVRHL.
OrthoDBEOG613070.

Enzyme and pathway databases

BioCycBMAL320389:GH97-1723-MONOMER.
UniPathwayUPA00185; UER00283.

Family and domain databases

HAMAPMF_00767. Arg_catab_AstE.
InterProIPR007036. Aste_AspA.
IPR016681. SuccinylGlu_desuccinylase.
[Graphical view]
PfamPF04952. AstE_AspA. 1 hit.
[Graphical view]
PIRSFPIRSF017020. AstE. 1 hit.
TIGRFAMsTIGR03242. arg_catab_astE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA3MLY6_BURM7
AccessionPrimary (citable) accession number: A3MLY6
Entry history
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: June 11, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)