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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Burkholderia mallei (strain NCTC 10247)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei204UniRule annotation1
Active sitei646UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCarbon dioxide fixation
LigandMagnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:BMA10247_1599
OrganismiBurkholderia mallei (strain NCTC 10247)
Taxonomic identifieri320389 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000255491 – 994Phosphoenolpyruvate carboxylaseAdd BLAST994

Proteomic databases

PRIDEiA3MLK7

Structurei

3D structure databases

ProteinModelPortaliA3MLK7
SMRiA3MLK7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

A3MLK7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSSGSARAT RRNAVSSSSA PAHAEPPARR AAKPARKLDG AAARPLAPTN
60 70 80 90 100
AASAKPQGRT REDKDRPLFE DIRYLGRLLG DVVREQEGDA VFDVVETIRQ
110 120 130 140 150
TAVKFRREDD KAAAQTLEKM LRKLTPEQTV SVVRAFSYFS HLANIAEDRH
160 170 180 190 200
HNRRRRIHAL AGSAAQAGTV AYALDKLKQA GDASSKTIKQ FFEGALIVPV
210 220 230 240 250
LTAHPTEVQR KSILDAQHDI ARLLAERDQP LTARELAHNE ALLRARVTTL
260 270 280 290 300
WQTRMLRDAR LTVADEIENA LSYYRATFLD ELPALYADIE EALAEHGLRA
310 320 330 340 350
RVPAFFQMGS WIGGDRDGNP NVTAATLDEA ISRQAAVIFE HYLEQVHKLG
360 370 380 390 400
AELSVSNLLV GASDALKALA AASPDQSPHR VDEPYRRALI GVYTRLAASA
410 420 430 440 450
RVRLGEGTVP VRSAGRGAAP VRATPYADAE EFAADLRVLT DSLALHHGES
460 470 480 490 500
LATPRLAPLM RAAEVFGFHL ASIDLRQSSD IHEAVVAELL ARGGVEADYA
510 520 530 540 550
ALPEADKLRV LLAALADPRP LRSPYLDYSD LAKSELGVLE RAHAIRAQFG
560 570 580 590 600
ARAVRNYIIS HTETVSDLVE VLLLQKETGL FEGTLGTPHA NARNGLMVIP
610 620 630 640 650
LFETIADLRN ASDIMRAFFA LPGVGELLAH QGHEQEVMLG YSDSNKDGGF
660 670 680 690 700
LTSNWELYRA ELALVDLFDE RGIKLRLFHG RGGTVGRGGG PTYQAILSQP
710 720 730 740 750
PGTVNGQIRL TEQGEVIASK FANPEIGRRN LETVVAATLE ATLAPHSNAP
760 770 780 790 800
KQLPAFEAAM QTLSDAAMAS YRALVYETPG FTDYFFSSTP ITEIAELNIG
810 820 830 840 850
SRPASRKLQD PKNRKIEDLR AIPWGFSWGQ CRLLLTGWYG FGSAVAAYLD
860 870 880 890 900
GAPDAAERGK RVALLKKMNK TWPFFANLLS NMDMVLAKTD LAVASRYAQL
910 920 930 940 950
VADKKLRKHV FERIVAEWHR TADALAEITG AHARLAANPL LARSIKNRFP
960 970 980 990
YLDPLNHLQV ELIKRHRAGD TNARLRRGIH LTINGIAAGL RNTG
Length:994
Mass (Da):108,735
Last modified:April 3, 2007 - v1
Checksum:i55D70FE099C4A788
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000548 Genomic DNA Translation: ABO07069.1
RefSeqiWP_004191560.1, NZ_CP007802.1

Genome annotation databases

EnsemblBacteriaiABO07069; ABO07069; BMA10247_1599
KEGGibmaz:BM44_1573
bmn:BMA10247_1599
PATRICifig|320389.8.peg.1757

Similar proteinsi

Entry informationi

Entry nameiCAPP_BURM7
AccessioniPrimary (citable) accession number: A3MLK7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 3, 2007
Last modified: May 23, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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