A3MKH3 (A3MKH3_BURM7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400
EC=1.8.4.12 HAMAP MF_01400

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase HAMAP MF_01400

Gene names

Name:	msrB HAMAP MF_01400 EMBL ABO04975.1
Ordered Locus Names:	BMA10247_1205

Organism

Burkholderia mallei (strain NCTC 10247) [Complete proteome] [HAMAP]

Taxonomic identifier

320389 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	151 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Cofactor	Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity. HAMAP MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family. HAMAP MF_01400

Ontologies

Keywords
Ligand	Metal-binding HAMAP MF_01400 Zinc HAMAP MF_01400
Molecular function	Oxidoreductase HAMAP MF_01400 SAAS SAAS002579 EMBL ABO04975.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	136	1	Nucleophile By similarity HAMAP MF_01400
	Metal binding	63	1	Zinc By similarity HAMAP MF_01400
	Metal binding	66	1	Zinc By similarity HAMAP MF_01400
	Metal binding	112	1	Zinc By similarity HAMAP MF_01400
	Metal binding	115	1	Zinc By similarity HAMAP MF_01400

Sequences

	Sequence		Length	Mass (Da)
	A3MKH3 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: 664A8A3FAC99BA07	FASTA	151	16,992
	10 20 30 40 50 60 MNSSGESKMS GDRDDPRYPY PKDDAELRRR LTPMQYEVTQ HAATEPPFTG EYTDTEDAGI 70 80 90 100 110 120 YHCVVCGTAL FESGAKFHSG CGWPSYFKPI DGEVIDEKMD YTHGMTRVEV RCNQCGAHLG 130 140 150 HVFEDGPRDK TGLRYCINSA ALNFEAKPER K

References

[1]	DeShazer D., Woods D.E., Nierman W.C. Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000548 Genomic DNA. Translation: ABO04975.1.
RefSeq	YP_001080759.1. NC_009080.1.
3D structure databases
ProteinModelPortal	A3MKH3.
SMR	A3MKH3. Positions 18-148.
ModBase	Search...
Protein-protein interaction databases
STRING	A3MKH3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4892103.
GenomeReviews	Gene locus BMA10247_1205 in contig CP000548_GR.
KEGG	bmn:BMA10247_1205.
PATRIC	19144833. VBIBurMal96640_3473.
TIGR	BMA10247_1205.
Phylogenomic databases
HOGENOM	HBG715255.
OMA	APLFRSD.
ProtClustDB	CLSK930638.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
KO	K07305.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A3MKH3_BURM7

Accession

Primary (citable) accession number: A3MKH3

Entry history

Integrated into UniProtKB/TrEMBL:	April 3, 2007
Last sequence update:	April 3, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)