SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A3MFQ4

- TRPC_BURM7

UniProt

A3MFQ4 - TRPC_BURM7

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Indole-3-glycerol phosphate synthase
Gene
trpC, BMA10247_A1913
Organism
Burkholderia mallei (strain NCTC 10247)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. indole-3-glycerol-phosphate synthase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciBMAL320389:GH97-5432-MONOMER.
UniPathwayiUPA00035; UER00043.

Names & Taxonomyi

Protein namesi
Recommended name:
Indole-3-glycerol phosphate synthase (EC:4.1.1.48)
Short name:
IGPS
Gene namesi
Name:trpC
Ordered Locus Names:BMA10247_A1913
OrganismiBurkholderia mallei (strain NCTC 10247)
Taxonomic identifieri320389 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
ProteomesiUP000002284: Chromosome II

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 261261Indole-3-glycerol phosphate synthaseUniRule annotation
PRO_1000018454Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi320389.BMA10247_A1913.

Structurei

3D structure databases

ProteinModelPortaliA3MFQ4.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpC family.

Phylogenomic databases

eggNOGiCOG0134.
HOGENOMiHOG000230463.
KOiK01609.
OMAiRKDFMFE.
OrthoDBiEOG6WT8JX.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00134_B. IGPS_B.
InterProiIPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00218. IGPS. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
PROSITEiPS00614. IGPS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A3MFQ4-1 [UniParc]FASTAAdd to Basket

« Hide

MSDILDKIIA VKREEIAAAL ESAPLEELKV QASARDSRDF VGALRDKHAA    50
GHAAVIAEVK KASPSKGVLR EHFVPADIAR SYAQHGAACL SVLTDERFFQ 100
GSARYLEQAR AACTLPVLRK DFIVDAYQLL EARAMGADAI LLIAAALDTP 150
LMIDLEAYAH SLGLAVLVEV HNRGELDEAL KLKTPFVGIN NRNLRTFETT 200
IDTTLGMLDA IPDDRIVVTE SGILSRADVE RMEAAGVHTF LVGEAFMRAE 250
NPGAELARMF F 261
Length:261
Mass (Da):28,383
Last modified:April 3, 2007 - v1
Checksum:iB72B5A0EA837CB29
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000547 Genomic DNA. Translation: ABO03008.1.
RefSeqiYP_001079090.1. NC_009079.1.

Genome annotation databases

EnsemblBacteriaiABO03008; ABO03008; BMA10247_A1913.
GeneIDi4890926.
KEGGibmn:BMA10247_A1913.
PATRICi19141429. VBIBurMal96640_1784.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000547 Genomic DNA. Translation: ABO03008.1 .
RefSeqi YP_001079090.1. NC_009079.1.

3D structure databases

ProteinModelPortali A3MFQ4.
ModBasei Search...

Protein-protein interaction databases

STRINGi 320389.BMA10247_A1913.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABO03008 ; ABO03008 ; BMA10247_A1913 .
GeneIDi 4890926.
KEGGi bmn:BMA10247_A1913.
PATRICi 19141429. VBIBurMal96640_1784.

Phylogenomic databases

eggNOGi COG0134.
HOGENOMi HOG000230463.
KOi K01609.
OMAi RKDFMFE.
OrthoDBi EOG6WT8JX.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00043 .
BioCyci BMAL320389:GH97-5432-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00134_B. IGPS_B.
InterProi IPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00218. IGPS. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
PROSITEi PS00614. IGPS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. DeShazer D., Woods D.E., Nierman W.C.
    Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCTC 10247.

Entry informationi

Entry nameiTRPC_BURM7
AccessioniPrimary (citable) accession number: A3MFQ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 3, 2007
Last modified: May 14, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi