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A3MFQ4

- TRPC_BURM7

UniProt

A3MFQ4 - TRPC_BURM7

Protein

Indole-3-glycerol phosphate synthase

Gene

trpC

Organism
Burkholderia mallei (strain NCTC 10247)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 45 (01 Oct 2014)
      Sequence version 1 (03 Apr 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. indole-3-glycerol-phosphate synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    BioCyciBMAL320389:GH97-5432-MONOMER.
    UniPathwayiUPA00035; UER00043.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Indole-3-glycerol phosphate synthaseUniRule annotation (EC:4.1.1.48UniRule annotation)
    Short name:
    IGPSUniRule annotation
    Gene namesi
    Name:trpCUniRule annotation
    Ordered Locus Names:BMA10247_A1913
    OrganismiBurkholderia mallei (strain NCTC 10247)
    Taxonomic identifieri320389 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
    ProteomesiUP000002284: Chromosome II

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 261261Indole-3-glycerol phosphate synthasePRO_1000018454Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi320389.BMA10247_A1913.

    Structurei

    3D structure databases

    ProteinModelPortaliA3MFQ4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpC family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0134.
    HOGENOMiHOG000230463.
    KOiK01609.
    OMAiRKDFMFE.
    OrthoDBiEOG6WT8JX.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00134_B. IGPS_B.
    InterProiIPR013785. Aldolase_TIM.
    IPR013798. Indole-3-glycerol_P_synth.
    IPR001468. Indole-3-GlycerolPSynthase_CS.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00218. IGPS. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.
    PROSITEiPS00614. IGPS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A3MFQ4-1 [UniParc]FASTAAdd to Basket

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    MSDILDKIIA VKREEIAAAL ESAPLEELKV QASARDSRDF VGALRDKHAA    50
    GHAAVIAEVK KASPSKGVLR EHFVPADIAR SYAQHGAACL SVLTDERFFQ 100
    GSARYLEQAR AACTLPVLRK DFIVDAYQLL EARAMGADAI LLIAAALDTP 150
    LMIDLEAYAH SLGLAVLVEV HNRGELDEAL KLKTPFVGIN NRNLRTFETT 200
    IDTTLGMLDA IPDDRIVVTE SGILSRADVE RMEAAGVHTF LVGEAFMRAE 250
    NPGAELARMF F 261
    Length:261
    Mass (Da):28,383
    Last modified:April 3, 2007 - v1
    Checksum:iB72B5A0EA837CB29
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000547 Genomic DNA. Translation: ABO03008.1.
    RefSeqiYP_001079090.1. NC_009079.1.

    Genome annotation databases

    EnsemblBacteriaiABO03008; ABO03008; BMA10247_A1913.
    GeneIDi4890926.
    KEGGibmn:BMA10247_A1913.
    PATRICi19141429. VBIBurMal96640_1784.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000547 Genomic DNA. Translation: ABO03008.1 .
    RefSeqi YP_001079090.1. NC_009079.1.

    3D structure databases

    ProteinModelPortali A3MFQ4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 320389.BMA10247_A1913.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABO03008 ; ABO03008 ; BMA10247_A1913 .
    GeneIDi 4890926.
    KEGGi bmn:BMA10247_A1913.
    PATRICi 19141429. VBIBurMal96640_1784.

    Phylogenomic databases

    eggNOGi COG0134.
    HOGENOMi HOG000230463.
    KOi K01609.
    OMAi RKDFMFE.
    OrthoDBi EOG6WT8JX.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00043 .
    BioCyci BMAL320389:GH97-5432-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00134_B. IGPS_B.
    InterProi IPR013785. Aldolase_TIM.
    IPR013798. Indole-3-glycerol_P_synth.
    IPR001468. Indole-3-GlycerolPSynthase_CS.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00218. IGPS. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    PROSITEi PS00614. IGPS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. DeShazer D., Woods D.E., Nierman W.C.
      Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NCTC 10247.

    Entry informationi

    Entry nameiTRPC_BURM7
    AccessioniPrimary (citable) accession number: A3MFQ4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: April 3, 2007
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3