Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A3MA94 (CAPP_ACIBT) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:A1S_3449
OrganismAcinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) [Complete proteome] [HAMAP]
Taxonomic identifier400667 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex

Protein attributes

Sequence length894 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 894894Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_1000025542

Sites

Active site1431 By similarity
Active site5561 By similarity

Sequences

Sequence LengthMass (Da)Tools
A3MA94 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: 84C447D1F8F14990

FASTA894102,087
        10         20         30         40         50         60 
MVQQIDAPLR EDVRLLGNLL GETLKQHAGQ ELFNQIEQIR ALAKGARDGQ AEAEKQLEQL 

        70         80         90        100        110        120 
FLELPDEELL PLTRAFSHFL NFANIAEQYH VVRSRRQAEF DPDANSPNPL VHLFKKFKDK 

       130        140        150        160        170        180 
NISTEKLFQQ ICDLKIELVL TAHPTEVSRR TLIQKYDDIN ACLSQLDQQK LTPRERQNAL 

       190        200        210        220        230        240 
ANLKQQISSA WQTDEIRQHR PTPVDEAKWG FATIEQTLWN AVPKFIRELN ELVQDNCQQN 

       250        260        270        280        290        300 
LPLHIAPVRF ASWMGGDRDG NPNVTHQITQ EVLWLSRWQA ADLYLRDIEN LRWELSIQSC 

       310        320        330        340        350        360 
SEEMVQAIGS PHPEPYREYL RATRERLKAT RHWLAQRLQG LEADDSNVIK SKDELLQPLL 

       370        380        390        400        410        420 
LCYRSLIDSN LPEIANGQLL DFIYRVNCFG IELLKLDIRQ ESGRHRQAIS AITEYLGLGN 

       430        440        450        460        470        480 
FESWTEQARQ NFLIQELQSK RPLLPKYINE PEGSLIGHPD VQEVFATMRT LADQPPESLG 

       490        500        510        520        530        540 
AYIISMAEYP SDVLAVLLLQ KEAGIQHPLR VVPLFETLKD LDGAATTMNT LFNMHWYKQH 

       550        560        570        580        590        600 
IQGKHEVMIG YSDSAKDAGF MSANWAQYRA QEELTAIARK HGVQLTLFHG RGGSISRGGA 

       610        620        630        640        650        660 
PTQQALFSQP PGSISGAIRV TEQGEMIRFK FGLEGIAMQN LEIYTAATLE ATLLPPPEPK 

       670        680        690        700        710        720 
AEWRELMNRM TDHSVKVYRQ TVRENPHFVK YLRTVTPELE LQMLPLGSRP AKRKVSGGIE 

       730        740        750        760        770        780 
SLRAIPWVFA WTQIRLMLPA WLGTGAAINE VIADQQKATL DEMLQQWPYF QTLIDMLEMV 

       790        800        810        820        830        840 
LSKADANIAL YYESHLTEDE DLKVLGNQLR QRLKDAVETL LTLKDESKLL SDNEVLDQSM 

       850        860        870        880        890 
QVRKPYLLPL HLLQAELMKR RRDYLAERQA EHTPVDHALM VSIAGIAAGL RNTG 

« Hide

References

[1]"New insights into Acinetobacter baumannii pathogenesis revealed by high-density pyrosequencing and transposon mutagenesis."
Smith M.G., Gianoulis T.A., Pukatzki S., Mekalanos J.J., Ornston L.N., Gerstein M., Snyder M.
Genes Dev. 21:601-614(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17978 / NCDC KC 755.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000521 Genomic DNA. Translation: ABO13838.1.
RefSeqYP_001086440.1. NC_009085.1.

3D structure databases

ProteinModelPortalA3MA94.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING400667.A1S_3449.

Proteomic databases

PRIDEA3MA94.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABO13838; ABO13838; A1S_3449.
GeneID4920052.
KEGGacb:A1S_3449.
PATRIC20723240. VBIAciBau103176_3479.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238648.
KOK01595.
OMAAIPWVFG.
OrthoDBEOG6TJ7T8.
ProtClustDBPRK00009.

Enzyme and pathway databases

BioCycABAU400667:GI0Q-3442-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_ACIBT
AccessionPrimary (citable) accession number: A3MA94
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 3, 2007
Last modified: February 19, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families