Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot A3M7W9 (F16PA_ACIBT)

Last modified October 13, 2009. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    Fructose-1,6-bisphosphatase class 1
      Short name=FBPase class 1
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Gene names
Name: fbp
Ordered Locus Names: A1S_2596
OrganismAcinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) [Complete proteome] [HAMAP]
Taxonomic identifier400667 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Hide | Top

Protein attributes

Sequence length323 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

Hide | Top

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the FBPase class 1 family.

Hide | Top

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 323323Fructose-1,6-bisphosphatase class 1 HAMAP MF_01855
PRO_0000364448

Regions

Region110 – 1134Substrate binding By similarity

Sites

Metal binding881Magnesium 1 By similarity
Metal binding1071Magnesium 1 By similarity
Metal binding1071Magnesium 2 By similarity
Metal binding1091Magnesium 1; via carbonyl oxygen By similarity
Metal binding1101Magnesium 2 By similarity
Metal binding2721Magnesium 2 By similarity
Binding site2001Substrate By similarity

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
A3M7W9-1 [UniParc].

Last modified September 2, 2008. Version 2.
Checksum: 843661906F2784E8

FASTA32335,472
        10         20         30         40         50         60 
MSNLTLSQFL QQEKGNLTPE LAQVIDTIAA TCKTIDQALQ KGALAGILGS AGNENVQGET 

        70         80         90        100        110        120 
QKKLDVISND YLIDALKVHP HVGGLASEEL DDFTLAQENG EYLVLFDPLD GSSNIDINMC 

       130        140        150        160        170        180 
VGTIFSILPA KNAVTQAQDF MQAGTQQVAA GYVLYGPSTM MALTVGNGVA FFTLDPETQT 

       190        200        210        220        230        240 
FLLTTENVQV SADTQEFAIN ASNQRHWEQP VKQYIEELLA GKTSVREKDF NMRWVACMVG 

       250        260        270        280        290        300 
DVHRILCRGG IFLYPYDLKD PKKAGRLRLM YEANPMSMLI EQAGGASTTG RVRILEIEPT 

       310        320 
ELHQRVPVII GSKNEVERVT SYH

« Hide

Hide | Top

References

[1]"New insights into Acinetobacter baumannii pathogenesis revealed by high-density pyrosequencing and transposon mutagenesis."
Smith M.G., Gianoulis T.A., Pukatzki S., Mekalanos J.J., Ornston L.N., Gerstein M., Snyder M.
Genes Dev. 21:601-614(2007) [PubMed: 17344419] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Hide | Top

Cross-references

Sequence databases

CP000521 Genomic DNA. Translation: ABO13013.2.
RefSeqYP_001085615.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA3M7W9.

Genome annotation databases

GeneID4917608.
GenomeReviewsGene locus A1S_2596 in contig CP000521_GR.
KEGGacb:A1S_2596.
NMPDRfig|400667.4.peg.2699.

Organism-specific databases

CMRSearch...

Family and domain databases

HAMAPMF_01855.
[Tree]
InterProIPR000146. Fructose_bisphosphatase.
IPR020548. Fructose_bisphosphatase_AS.
[Graphical view]
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PRINTSPR00115. F16BPHPHTASE.
PROSITEPS00124. FBPASE. False negative.
[Graphical view]
ProtoNetSearch...

Hide | Top

Entry information

Entry nameF16PA_ACIBT
AccessionPrimary (citable) accession number: A3M7W9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: September 2, 2008
Last modified: October 13, 2009
This is version 27 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Hide | Top

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents