Reviewed, UniProtKB/Swiss-Prot A3M504 (KCY_ACIBT)

Names and origin

Protein names

Recommended name:
    Cytidylate kinase
      Short name=CK
    EC=2.7.4.14
Alternative name(s):
    Cytidine monophosphate kinase
      Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	A1S_1571

Organism

Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) [Complete proteome] [HAMAP]

Taxonomic identifier

400667 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyrimidine nucleotide metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP cytidylate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 228	228	Cytidylate kinase HAMAP MF_00238		PRO_1000100641
Regions
	Nucleotide binding	10 – 18	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	A3M504-1 [UniParc]. Last modified September 2, 2008. Version 2. Checksum: 210894568B80D5FD	FASTA	228	25,236
	10 20 30 40 50 60 MTVQIITIDG PSGSGKGTLA AKLAAYYQFH LLDSGALYRL LGLSLHKHDL LEKLDSHLDE 70 80 90 100 110 120 CVNYARQLNI KFETSAEGTL VFLDGEDVTQ TIRTERVGEY ASKVAAIPEL RQALFERQRA 130 140 150 160 170 180 FAQTPGLVAD GRDMATSIFP EANAKIYLTA SAESRAERRV KQLQGMGLDA KINDILANIQ 190 200 210 220 ARDKRDMERE VAPLKPAADA YIIDSSELTI DQVFKLMVDY VNSRTVSN

References

[1]

"New insights into Acinetobacter baumannii pathogenesis revealed by high-density pyrosequencing and transposon mutagenesis." Smith M.G., Gianoulis T.A., Pukatzki S., Mekalanos J.J., Ornston L.N., Gerstein M., Snyder M. Genes Dev. 21:601-614(2007) [PubMed: 17344419] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000521 Genomic DNA. Translation: ABO11998.2.
RefSeq	YP_001084600.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A3M504.
Genome annotation databases
GeneID	4917197.
GenomeReviews	Gene locus A1S_1571 in contig CP000521_GR.
KEGG	acb:A1S_1571.
NMPDR	fig|400667.4.peg.1629.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_00238. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kin_d. [Graphical view]
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_ACIBT

Accession

Primary (citable) accession number: A3M504

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	September 2, 2008
Last modified:	September 1, 2009
This is version 22 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)