A3M3C7 (MTGA_ACIBT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Monofunctional biosynthetic peptidoglycan transglycosylase
Short name=Monofunctional TGase
EC=2.4.2.-

Gene names

Name:	mtgA
Ordered Locus Names:	A1S_0989

Organism

Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) [Complete proteome] [HAMAP]

Taxonomic identifier

400667 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter › Acinetobacter calcoaceticus/baumannii complex › Acinetobacter baumannii

Protein attributes

Sequence length	225 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Cell wall formation By similarity. HAMAP-Rule MF_00766
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00766
Subcellular location	Cell membrane; Single-pass membrane protein Potential HAMAP-Rule MF_00766.
Sequence similarities	Belongs to the glycosyltransferase 51 family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	peptidoglycan biosynthetic process Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan-based cell wall Inferred from electronic annotation. Source: InterPro plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	transferase activity, transferring pentosyl groups Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 225	225	Monofunctional biosynthetic peptidoglycan transglycosylase HAMAP-Rule MF_00766		PRO_1000133583
Regions
	Transmembrane	8 – 28	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	A3M3C7 [UniParc]. Last modified September 2, 2008. Version 2. Checksum: 6E64E8A1B1537BBA	FASTA	225	26,723
	10 20 30 40 50 60 MKAFIVRVLL IFIGAILFIQ LWIFSSLVWW RTHEVDTTMF MRIDYWSDTS EPIIHEWLDY 70 80 90 100 110 120 DDISDNFKHA ILAGEDAKFI HHHGFDWDGI RFALERNNEQ GEVVAGGSTV SQQLAKNLFL 130 140 150 160 170 180 YNKRSFIRKG QETVATWMME RMWSKRRILE VYMNSVEFGK NLYGVEAAAQ YYYGKSAKNL 190 200 210 220 TREQAAFLAA LLPDPKYYQD HRNDRKLQYR KRVILRYMNS TQIPE

References

[1]

"New insights into Acinetobacter baumannii pathogenesis revealed by high-density pyrosequencing and transposon mutagenesis." Smith M.G., Gianoulis T.A., Pukatzki S., Mekalanos J.J., Ornston L.N., Gerstein M., Snyder M. Genes Dev. 21:601-614(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17978 / NCDC KC 755.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000521 Genomic DNA. Translation: ABO11421.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	400667.A1S_0989.
Protein family/group databases
CAZy	GT51. Glycosyltransferase Family 51.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	20718180. VBIAciBau103176_1004.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0744.
HOGENOM	HOG000288116.
ProtClustDB	CLSK707184.
Enzyme and pathway databases
BioCyc	ABAU400667:GI0Q-977-MONOMER.
UniPathway	UPA00219.
Family and domain databases
HAMAP	MF_00766. Mono_pep_trsgly.
InterPro	IPR001264. Glyco_trans_51. IPR011812. Mono_pep_trsgly. [Graphical view]
Pfam	PF00912. Transgly. 1 hit. [Graphical view]
TIGRFAMs	TIGR02070. mono_pep_trsgly. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MTGA_ACIBT

Accession

Primary (citable) accession number: A3M3C7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	September 2, 2008
Last modified:	May 29, 2013
This is version 53 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program