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Protein

Monofunctional biosynthetic peptidoglycan transglycosylase

Gene

mtgA

Organism
Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cell wall formation.UniRule annotation

Pathway:ipeptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciABAU400667:GI0Q-977-MONOMER.
UniPathwayiUPA00219.

Protein family/group databases

CAZyiGT51. Glycosyltransferase Family 51.

Names & Taxonomyi

Protein namesi
Recommended name:
Monofunctional biosynthetic peptidoglycan transglycosylaseUniRule annotation (EC:2.4.2.-UniRule annotation)
Short name:
Monofunctional TGaseUniRule annotation
Gene namesi
Name:mtgAUniRule annotation
Ordered Locus Names:A1S_0989
OrganismiAcinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377)
Taxonomic identifieri400667 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
ProteomesiUP000006737 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei8 – 2821HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 225225Monofunctional biosynthetic peptidoglycan transglycosylasePRO_1000133583Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 51 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0744.
HOGENOMiHOG000288116.
OrthoDBiEOG6HMXCD.

Family and domain databases

HAMAPiMF_00766. Mono_pep_trsgly.
InterProiIPR001264. Glyco_trans_51.
IPR023346. Lysozyme-like_dom.
IPR011812. Mono_pep_trsgly.
[Graphical view]
PfamiPF00912. Transgly. 1 hit.
[Graphical view]
SUPFAMiSSF53955. SSF53955. 1 hit.
TIGRFAMsiTIGR02070. mono_pep_trsgly. 1 hit.

Sequencei

Sequence statusi: Complete.

A3M3C7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAFIVRVLL IFIGAILFIQ LWIFSSLVWW RTHEVDTTMF MRIDYWSDTS
60 70 80 90 100
EPIIHEWLDY DDISDNFKHA ILAGEDAKFI HHHGFDWDGI RFALERNNEQ
110 120 130 140 150
GEVVAGGSTV SQQLAKNLFL YNKRSFIRKG QETVATWMME RMWSKRRILE
160 170 180 190 200
VYMNSVEFGK NLYGVEAAAQ YYYGKSAKNL TREQAAFLAA LLPDPKYYQD
210 220
HRNDRKLQYR KRVILRYMNS TQIPE
Length:225
Mass (Da):26,723
Last modified:September 2, 2008 - v2
Checksum:i6E64E8A1B1537BBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000521 Genomic DNA. Translation: ABO11421.2.

Genome annotation databases

EnsemblBacteriaiABO11421; ABO11421; A1S_0989.
PATRICi20718180. VBIAciBau103176_1004.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000521 Genomic DNA. Translation: ABO11421.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGT51. Glycosyltransferase Family 51.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABO11421; ABO11421; A1S_0989.
PATRICi20718180. VBIAciBau103176_1004.

Phylogenomic databases

eggNOGiCOG0744.
HOGENOMiHOG000288116.
OrthoDBiEOG6HMXCD.

Enzyme and pathway databases

UniPathwayiUPA00219.
BioCyciABAU400667:GI0Q-977-MONOMER.

Family and domain databases

HAMAPiMF_00766. Mono_pep_trsgly.
InterProiIPR001264. Glyco_trans_51.
IPR023346. Lysozyme-like_dom.
IPR011812. Mono_pep_trsgly.
[Graphical view]
PfamiPF00912. Transgly. 1 hit.
[Graphical view]
SUPFAMiSSF53955. SSF53955. 1 hit.
TIGRFAMsiTIGR02070. mono_pep_trsgly. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "New insights into Acinetobacter baumannii pathogenesis revealed by high-density pyrosequencing and transposon mutagenesis."
    Smith M.G., Gianoulis T.A., Pukatzki S., Mekalanos J.J., Ornston L.N., Gerstein M., Snyder M.
    Genes Dev. 21:601-614(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377.

Entry informationi

Entry nameiMTGA_ACIBT
AccessioniPrimary (citable) accession number: A3M3C7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 2, 2008
Last modified: June 24, 2015
This is version 64 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.