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A3M0C9 (RIFK_PICST) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Riboflavin kinase

EC=2.7.1.26
Alternative name(s):
Flavin mononucleotide kinase 1
Gene names
Name:FMN1
ORF Names:PICST_50354
OrganismScheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis) [Complete proteome]
Taxonomic identifier322104 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeScheffersomyces

Protein attributes

Sequence length178 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme By similarity.

Catalytic activity

ATP + riboflavin = ADP + FMN.

Cofactor

Zinc or magnesium By similarity.

Pathway

Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.

Sequence similarities

Belongs to the flavokinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 178178Riboflavin kinase
PRO_0000301849

Sites

Active site1161Nucleophile By similarity
Metal binding391Magnesium or zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
A3M0C9 [UniParc].

Last modified July 24, 2007. Version 2.
Checksum: 4D63EA7A0ABCDB2F

FASTA17820,327
        10         20         30         40         50         60 
MARPDTVIPD KPESPYPIVQ DSVVVSGFGR GSSELGIPTA NIPINDDLNQ LETGIYYGWC 

        70         80         90        100        110        120 
QLKPCTLPDE CKTRTNGREV IYNHGKNLRN DDLKVLPMVM SIGWNPFYHL KEKAAEVHIM 

       130        140        150        160        170 
HKFDDFFYGA QIKFNVLGYI RPELDYTTKE ALIEDINLDI KIALEALDRD AYQTYKDL 

« Hide

References

[1]"Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis."
Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A., Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S., Passoth V., Richardson P.M.
Nat. Biotechnol. 25:319-326(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000502 Genomic DNA. Translation: ABN68689.2.
RefSeqXP_001386718.2. XM_001386681.1.

3D structure databases

ProteinModelPortalA3M0C9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING4924.PICST_50354.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4841164.
KEGGpic:PICST_50354.

Phylogenomic databases

eggNOGCOG0196.
HOGENOMHOG000260803.
KOK00861.
OMALGWNPFY.
OrthoDBEOG7K3V05.

Enzyme and pathway databases

UniPathwayUPA00276; UER00406.

Family and domain databases

Gene3D2.40.30.30. 1 hit.
InterProIPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view]
PANTHERPTHR22749. PTHR22749. 1 hit.
PfamPF01687. Flavokinase. 1 hit.
[Graphical view]
SMARTSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMSSF82114. SSF82114. 2 hits.
ProtoNetSearch...

Entry information

Entry nameRIFK_PICST
AccessionPrimary (citable) accession number: A3M0C9
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: July 24, 2007
Last modified: January 22, 2014
This is version 46 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways