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Protein
Submitted name:

Alpha-ketoglutarate dehydrogenase

Gene

KGD1

Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-ketoglutarate dehydrogenaseImported (EC:1.2.4.2Imported)
Gene namesi
Name:KGD1Imported
ORF Names:PICST_79721Imported
OrganismiScheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)Imported
Taxonomic identifieri322104 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeScheffersomyces
ProteomesiUP000002258 Componenti: Chromosome 8

Interactioni

Protein-protein interaction databases

STRINGi4924.PICST_79721.

Structurei

3D structure databases

ProteinModelPortaliA3LZW8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000259586.
InParanoidiA3LZW8.
KOiK00164.
OMAiNCERLYC.
OrthoDBiEOG72G1GM.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

A3LZW8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKAFRNVVP RGQLLRASAR PSLRSMAPLT SSTSIRSTNS IRCFATGTDS
60 70 80 90 100
FLQGNNSNYI DEMYDAWRQD PSSVHASWNA YFKNIESSNI PPSQAFQAPP
110 120 130 140 150
TIVPTVSGGA AGFVPGSNPI SEDVVTHLKV QLLVRAYQVR GHQKAKIDPL
160 170 180 190 200
GISFGDNSDT PKELTLDYYG FTDVDLNKQI TLGPGILPRF AEAGKKSLTL
210 220 230 240 250
REIIENCEKL YCQSYGVEYV HIPSKEQCDW LRERIEIPQP FKYSADQKRQ
260 270 280 290 300
ILDRLIWSCS FESFLATKFP NDKRFGLEGA EAVVPGMKAL IDTSVEFGVE
310 320 330 340 350
DIVIGMPHRG RLNMLSNVVR KPNESIFSEF TGSKEFDEGS GDVKYHLGMN
360 370 380 390 400
YARPTTSGKF VNLSIVANPS HLEAEDGVVL GKTRAIQQYK NDIGDYKRAM
410 420 430 440 450
PILLHGDAAF AGQGVVYETM GFAHLPAYST GGTIHIIVNN QIGFTTDPRY
460 470 480 490 500
SRSTLYPSDI AKASNSPIFH VNADDVEACI FVFNLAAEWR ATFHSDVIID
510 520 530 540 550
VVGYRKHGHN ETDQPAFTQP LMYKKIAEKK SVLEYYTNQL IQEGTFTTED
560 570 580 590 600
ISEHKKWVWN LLEDYFAKSK EYVPTSREWL TTPWEDFKSP KELATEVLPH
610 620 630 640 650
LPTAVDEETL KKIGKAISEA PEGFEIHRNL KRILNTRNKT VETGEGIDWA
660 670 680 690 700
TGEALAFGTL ALEGYHVRVS GQDVERGTFS QRHAVLHDQQ SEKTYTPLNH
710 720 730 740 750
LSEEQGAFVI SNSSLSEYGV LGFEYGYSLT SPDALVQWEA QFGDFANTGQ
760 770 780 790 800
VIMDQFIASA ESKWKQRSGL VLSLPHGYDG QGPEHSSGRI ERYLQMCNED
810 820 830 840 850
QRYFPSPSKL ERQHQDCNFQ VAYPTTPANL FHLLRRQMHR QFRKPLALFF
860 870 880 890 900
SKSLLRHPLA RSDLSEFTND SHFQWIIEDA EYGKTIAPKE EIKRVVLCSG
910 920 930 940 950
QVFTALHKKR AAIEDKTTAF IKIEQVHPFP FAQLRDALDS HPNLEDLVWC
960 970 980 990 1000
QEEPLNMGSY SFVSPRITTT LAETENHKGL TLRYAGRDPS ASVAAGSKAM
1010
HTAQEEAFLN ETFQV
Length:1,015
Mass (Da):114,107
Last modified:July 24, 2007 - v2
Checksum:i4094E124207E0011
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000502 Genomic DNA. Translation: ABN68415.2.
RefSeqiXP_001386444.2. XM_001386407.1.

Genome annotation databases

GeneIDi4840878.
KEGGipic:PICST_79721.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000502 Genomic DNA. Translation: ABN68415.2.
RefSeqiXP_001386444.2. XM_001386407.1.

3D structure databases

ProteinModelPortaliA3LZW8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4924.PICST_79721.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4840878.
KEGGipic:PICST_79721.

Phylogenomic databases

HOGENOMiHOG000259586.
InParanoidiA3LZW8.
KOiK00164.
OMAiNCERLYC.
OrthoDBiEOG72G1GM.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545Imported.

Entry informationi

Entry nameiA3LZW8_PICST
AccessioniPrimary (citable) accession number: A3LZW8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: July 24, 2007
Last modified: April 1, 2015
This is version 57 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.