ID   A3LYK2_PICST            Unreviewed;       409 AA.
AC   A3LYK2;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2007, sequence version 2.
DT   13-SEP-2023, entry version 61.
DE   SubName: Full=Hyphally regulated cell wall protein {ECO:0000313|EMBL:ABN67654.2};
DE            EC=3.2.1.18 {ECO:0000313|EMBL:ABN67654.2};
DE   Flags: Fragment;
GN   Name=HYR6.2 {ECO:0000313|EMBL:ABN67654.2};
GN   ORFNames=PICST_3402 {ECO:0000313|EMBL:ABN67654.2};
OS   Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS   Y-11545) (Yeast) (Pichia stipitis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX   NCBI_TaxID=322104 {ECO:0000313|EMBL:ABN67654.2, ECO:0000313|Proteomes:UP000002258};
RN   [1] {ECO:0000313|EMBL:ABN67654.2, ECO:0000313|Proteomes:UP000002258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC   {ECO:0000313|Proteomes:UP000002258};
RX   PubMed=17334359; DOI=10.1038/nbt1290;
RA   Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA   Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA   Passoth V., Richardson P.M.;
RT   "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT   yeast Pichia stipitis.";
RL   Nat. Biotechnol. 25:319-326(2007).
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC       {ECO:0000256|ARBA:ARBA00004191}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000500; ABN67654.2; -; Genomic_DNA.
DR   RefSeq; XP_001385683.2; XM_001385646.1.
DR   AlphaFoldDB; A3LYK2; -.
DR   GeneID; 4840202; -.
DR   KEGG; pic:PICST_3402; -.
DR   HOGENOM; CLU_006199_3_1_1; -.
DR   InParanoid; A3LYK2; -.
DR   OMA; ANGSHKI; -.
DR   OrthoDB; 1997971at2759; -.
DR   Proteomes; UP000002258; Chromosome 6.
DR   GO; GO:0009277; C:fungal-type cell wall; IEA:UniProt.
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR008440; Agglutinin-like_ALS_rpt.
DR   InterPro; IPR021031; Hyphal-reg_cell_wall_N.
DR   Pfam; PF05792; Candida_ALS; 2.
DR   Pfam; PF11765; Hyphal_reg_CWP; 1.
PE   4: Predicted;
KW   Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW   Glycosidase {ECO:0000313|EMBL:ABN67654.2};
KW   Hydrolase {ECO:0000313|EMBL:ABN67654.2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002258};
KW   Secreted {ECO:0000256|ARBA:ARBA00022512}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..409
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002655700"
FT   DOMAIN          11..337
FT                   /note="Hyphally-regulated cell wall protein N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11765"
FT   NON_TER         409
FT                   /evidence="ECO:0000313|EMBL:ABN67654.2"
SQ   SEQUENCE   409 AA;  44143 MW;  E8F78BFEBBCEC888 CRC64;
     MLLFRSLVRV FLFATVALAF TVQKPKVDRG SINLSIGDIT IQSGSFWSIF DNTVSIFKGD
     LWVQKNAGFF ITSTNKLIGL KVELASGFGS IRNDGLIVFN SLVSITPSFY KLIGKSFLNS
     GEIFLVSSGY GVPTAALLAP IWKNTGSLTF FQNKRNNGVV SLGAPGLKIE NWGQICLFNE
     LYKQTTHIFG DGCITADQDS SIFFSNCLLD IDSRQTVYLA DSRSSVRAVA LAKPKTFKVA
     GFGNGNKIGL DLPLISPFSK SVIYNAKTGI LSLRVKGFWG QDFNIGLGYN SNKFKITTDN
     SLGLLSVPWG AVYYDGPVPN KQIPSNCQPC KPYPSPPTTT TTKTNAQTTK TSTWTGTFTT
     TVTETDTPGG TDTVIVEVPS TPNSQTTLTS TWTGTFTTTV TETDTPGGT
//