A3LW87 (A3LW87_PICST) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Uroporphyrinogen decarboxylase RuleBase RU000554
EC=4.1.1.37 RuleBase RU000554

Gene names

Name:	HEM12 EMBL ABN66922.1
ORF Names:	PICST_46716 EMBL ABN66922.1

Organism

Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis) [Complete proteome]

Taxonomic identifier

322104 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Scheffersomyces

Protein attributes

Sequence length	362 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Uroporphyrinogen III = coproporphyrinogen + 4 CO2. RuleBase RU000554
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen III from 5-aminolevulinate: step 4/4. RuleBase RU000554
Sequence similarities	Belongs to the uroporphyrinogen decarboxylase family. RuleBase RU004169

Ontologies

Keywords
Biological process	Porphyrin biosynthesis RuleBase RU000554
Molecular function	Decarboxylase RuleBase RU000554 Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	porphyrin-containing compound biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	uroporphyrinogen decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A3LW87 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: E4DE97CB546E1D3E	FASTA	362	41,142
	10 20 30 40 50 60 MPEFAPLKND LILRAARGEK VERPPIWIMR QAGRYLPEYH EAKGNRDFFE TCRDAEIASE 70 80 90 100 110 120 ITIQPVNHFD GLIDAAIIFS DILVIPQAMG FEIEMLEGKG PVFVAPLRSP DDLARVNFQP 130 140 150 160 170 180 DVLKSLDWAF KSITLTRTKL NGRVPLLGFV GAPWTLLVYM TEGQGSKMFR FVKEWIYKYT 190 200 210 220 230 240 EESHKLLQAI TDACVEFLAQ QVVAGAQMLQ VFESWAGELG PREFDEFSLP YLRQIAEKLP 250 260 270 280 290 300 KRLVELGVTE KIPLTVFAKG AWYALDDLCE SGYDTVSLDW LYKPEDAVKV VNNRRITLQG 310 320 330 340 350 360 NLDPGIMYGS DEVISQKVEE MIKGFGGGKQ NYIINFGHGT HPFMKPEKIE HFLKECHKYG SQ

References

[1]

"Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis." Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A., Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S., Passoth V., Richardson P.M. Nat. Biotechnol. 25:319-326(2007) [PubMed: 17334359] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000499 Genomic DNA. Translation: ABN66922.1.
RefSeq	XP_001384951.1. XM_001384914.1.
3D structure databases
ProteinModelPortal	A3LW87.
ModBase	Search...
Protein-protein interaction databases
STRING	A3LW87.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4839596.
GenomeReviews	Gene locus HEM12 in contig CP000499_GR.
KEGG	pic:PICST_46716.
Phylogenomic databases
eggNOG	fuNOG04392.
HOGENOM	HBG628392.
OMA	KGPTFPE.
OrthoDB	EOG447K2V.
Family and domain databases
HAMAP	MF_00218. URO_D. [Tree]
InterPro	IPR006361. Uroporphyrinogen_deCO2ase_HemE. IPR000257. Uroporphyrinogen_deCOase. [Graphical view]
KO	K01599.
PANTHER	PTHR21091:SF2. HemE. 1 hit.
Pfam	PF01208. URO-D. 1 hit. [Graphical view]
TIGRFAMs	TIGR01464. HemE. 1 hit.
PROSITE	PS00906. UROD_1. 1 hit. PS00907. UROD_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A3LW87_PICST

Accession

Primary (citable) accession number: A3LW87

Entry history

Integrated into UniProtKB/TrEMBL:	April 3, 2007
Last sequence update:	April 3, 2007
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)