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A3LW52

- OCA1_PICST

UniProt

A3LW52 - OCA1_PICST

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Protein
Putative tyrosine-protein phosphatase OCA1
Gene
OCA1, PICST_46361
Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Putative tyrosine-protein phosphatase required for protection against superoxide stress By similarity.

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei146 – 1461Phosphocysteine intermediate By similarity

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC

GO - Biological processi

  1. response to stress Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase OCA1 (EC:3.1.3.48)
Gene namesi
Name:OCA1
ORF Names:PICST_46361
OrganismiScheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
Taxonomic identifieri322104 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeScheffersomyces
ProteomesiUP000002258: Chromosome 5

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 212212Putative tyrosine-protein phosphatase OCA1
PRO_0000333394Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi4924.PICST_46361.

Structurei

3D structure databases

ProteinModelPortaliA3LW52.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2365.
HOGENOMiHOG000188365.
KOiK18043.
OMAiNINWELA.
OrthoDBiEOG7Z0K6V.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR020428. Tyr_Pase_dualsp-Pase_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
PRINTSiPR01911. PFDSPHPHTASE.
SUPFAMiSSF52799. SSF52799. 1 hit.

Sequencei

Sequence statusi: Complete.

A3LW52-1 [UniParc]FASTAAdd to Basket

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MSNKDTSILK GNVDHEEADS NPKLRKIGRP PALRIIPPLN FCPVERQLYR    50
SGQPSAINQS FLEQLNLKTI LWLASEEPQD DFLEFSNDHN INIEFVGIIN 100
EFSNYQNYNT NQTLTVNPWD ALNEQTIKRA LELIVNRENY PLLVCCGMGR 150
HRTGTVIGCL RRLQGWNLAS VSEEYRRFTG ARGGRILVEL LIESFDIGSV 200
EIDPSKVPDW LT 212
Length:212
Mass (Da):24,185
Last modified:April 3, 2007 - v1
Checksum:i4CBBA80963E04A6D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000499 Genomic DNA. Translation: ABN66907.1.
RefSeqiXP_001384936.1. XM_001384899.1.

Genome annotation databases

GeneIDi4839644.
KEGGipic:PICST_46361.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000499 Genomic DNA. Translation: ABN66907.1 .
RefSeqi XP_001384936.1. XM_001384899.1.

3D structure databases

ProteinModelPortali A3LW52.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 4924.PICST_46361.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4839644.
KEGGi pic:PICST_46361.

Phylogenomic databases

eggNOGi COG2365.
HOGENOMi HOG000188365.
KOi K18043.
OMAi NINWELA.
OrthoDBi EOG7Z0K6V.

Family and domain databases

Gene3Di 3.90.190.10. 1 hit.
InterProi IPR029021. Prot-tyrosine_phosphatase-like.
IPR020428. Tyr_Pase_dualsp-Pase_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view ]
Pfami PF03162. Y_phosphatase2. 1 hit.
[Graphical view ]
PRINTSi PR01911. PFDSPHPHTASE.
SUPFAMi SSF52799. SSF52799. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545.

Entry informationi

Entry nameiOCA1_PICST
AccessioniPrimary (citable) accession number: A3LW52
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 3, 2007
Last modified: June 11, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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