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A3LW52 (OCA1_PICST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative tyrosine-protein phosphatase OCA1
EC=3.1.3.48
Gene names
Name:OCA1
ORF Names:PICST_46361
OrganismScheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis) [Complete proteome]
Taxonomic identifier322104 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Scheffersomyces ›

Protein attributes

Sequence length212 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Putative tyrosine-protein phosphatase required for protection against superoxide stress By similarity.

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family.

Ontologies

Keywords
   Biological processStress response
   Cellular componentCytoplasm
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpeptidyl-tyrosine dephosphorylation

Inferred from electronic annotation. Source: GOC

response to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionprotein tyrosine phosphatase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 212212Putative tyrosine-protein phosphatase OCA1
PRO_0000333394

Sites

Active site1461Phosphocysteine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
A3LW52 [UniParc].

Last modified April 3, 2007. Version 1.
Checksum: 4CBBA80963E04A6D

FASTA21224,185
        10         20         30         40         50         60 
MSNKDTSILK GNVDHEEADS NPKLRKIGRP PALRIIPPLN FCPVERQLYR SGQPSAINQS 

        70         80         90        100        110        120 
FLEQLNLKTI LWLASEEPQD DFLEFSNDHN INIEFVGIIN EFSNYQNYNT NQTLTVNPWD 

       130        140        150        160        170        180 
ALNEQTIKRA LELIVNRENY PLLVCCGMGR HRTGTVIGCL RRLQGWNLAS VSEEYRRFTG 

       190        200        210 
ARGGRILVEL LIESFDIGSV EIDPSKVPDW LT

« Hide

References

[1]"Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis."
Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A., Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S., Passoth V., Richardson P.M.
Nat. Biotechnol. 25:319-326(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000499 Genomic DNA. Translation: ABN66907.1.
RefSeqXP_001384936.1. XM_001384899.1.

3D structure databases

ProteinModelPortalA3LW52.
ModBaseSearch...

Protein-protein interaction databases

STRING4924.PICST_46361.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4839644.
KEGGpic:PICST_46361.

Phylogenomic databases

eggNOGCOG2365.
HOGENOMHOG000188365.
OMAHNINIEF.
OrthoDBEOG40VZZZ.

Family and domain databases

InterProIPR020428. Tyr_Pase_dualsp-Pase_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
PRINTSPR01911. PFDSPHPHTASE.
PROSITEPS00383. TYR_PHOSPHATASE_1. False negative.
PS50056. TYR_PHOSPHATASE_2. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameOCA1_PICST
AccessionPrimary (citable) accession number: A3LW52
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 3, 2007
Last modified: May 1, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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