A3LV77 (A3LV77_PICST) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
5-aminolevulinate synthase, mitochondrial (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) EMBL ABN67078.1
EC=2.3.1.37 EMBL ABN67078.1

Gene names

Name:	HEM1 EMBL ABN67078.1
ORF Names:	PICST_89623 EMBL ABN67078.1

Organism

Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis) [Complete proteome]

Taxonomic identifier

322104 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Scheffersomyces

Protein attributes

Sequence length	573 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU003693
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU003693

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU003693
Molecular function	Acyltransferase EMBL ABN67078.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrapyrrole biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-aminolevulinate synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring nitrogenous groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A3LV77 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: 3FA0E862F0CEFF57	FASTA	573	62,086
	10 20 30 40 50 60 MESLTRASMA VCPFVKASSA QTLRQISRSS SGGLASQARQ CPFMGAAMRA QERNYSSATR 70 80 90 100 110 120 PARATASTAA TSSATASSPY AFKGEDLTAS DISLGSNESA FDFHGYMADE LHRKREDKSY 130 140 150 160 170 180 RFFNNINRLA QDFPKAHRSN EEDRVTVWCS NDYLGMGKNT NTLNEMKRVL EVYGSGAGGT 190 200 210 220 230 240 RNIAGHNVHA IKLESELAAL HKHEAALVFS SCFVCNDAVL SLFGQKIKDL VIFSDVLNHA 250 260 270 280 290 300 SMIQGIKNSR AKKHIFKHND LADLEAKLAQ YPKSTPKLIA FESVYSMCGS IAPIEAICDL 310 320 330 340 350 360 AEKYGALTFL DEVHAVGMYG PHGAGVAEHL NFEAHLKSGI EHPDIKTVMS RVDMVTGTLG 370 380 390 400 410 420 KAFGTVGGYI TGKASMIDWF RSYAPGFIFT TSLPPAIMAG SSASIRYQRA TLQDRIAQQK 430 440 450 460 470 480 NTRYVKNNLN AIGIPVMPNP AHIVPVLIGN AADAKKASDL LLNKHDIYVQ AINFPTVPIG 490 500 510 520 530 540 EERLRITPTP GHGPELSNQL IEAVDSVFNE LNLSRISDWE RNGGLCGVGE RDAAPIEHIW 550 560 570 TDAQLALSDS DLNPNVFDPV VAPIGVSSGV SSY

References

[1]

"Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis." Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A., Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S., Passoth V., Richardson P.M. Nat. Biotechnol. 25:319-326(2007) [PubMed: 17334359] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000499 Genomic DNA. Translation: ABN67078.1.
RefSeq	XP_001385107.1. XM_001385070.1.
3D structure databases
ProteinModelPortal	A3LV77.
ModBase	Search...
Protein-protein interaction databases
STRING	A3LV77.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4839518.
GenomeReviews	Gene locus HEM1 in contig CP000499_GR.
KEGG	pic:PICST_89623.
Phylogenomic databases
eggNOG	fuNOG07159.
HOGENOM	HBG649839.
OMA	HLVKAMD.
OrthoDB	EOG412QDQ.
Family and domain databases
InterPro	IPR010961. 4pyrrol_synth_NH2levulA_synth. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00643.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01821. 5aminolev_synth. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A3LV77_PICST

Accession

Primary (citable) accession number: A3LV77

Entry history

Integrated into UniProtKB/TrEMBL:	April 3, 2007
Last sequence update:	April 3, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)