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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

GPD2

Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei134NADUniRule annotation1
Binding sitei157SubstrateUniRule annotation1
Binding sitei190NAD; via amide nitrogenUniRule annotation1
Active sitei250Proton acceptorUniRule annotation1
Binding sitei315NADUniRule annotation1
Binding sitei344NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi46 – 51NADUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
Name:GPD2Imported
ORF Names:PICST_83071Imported
OrganismiScheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)Imported
Taxonomic identifieri322104 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeScheffersomyces
Proteomesi

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi322104.XP_001384566.2

Structurei

3D structure databases

ProteinModelPortaliA3LU81
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 206NAD_Gly3P_dh_NInterPro annotationAdd BLAST165
Domaini239 – 383NAD_Gly3P_dh_CInterPro annotationAdd BLAST145

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni315 – 316Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2711 Eukaryota
COG0240 LUCA
HOGENOMiHOG000246855
InParanoidiA3LU81
KOiK00006
OMAiADCVEIC
OrthoDBiEOG092C3ZQP

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR006168 G3P_DH_NAD-dep
IPR006109 G3P_DH_NAD-dep_C
IPR017751 G3P_DH_NAD-dep_euk
IPR011128 G3P_DH_NAD-dep_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF07479 NAD_Gly3P_dh_C, 1 hit
PF01210 NAD_Gly3P_dh_N, 1 hit
PIRSFiPIRSF000114 Glycerol-3-P_dh, 1 hit
PRINTSiPR00077 GPDHDRGNASE
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR03376 glycerol3P_DH, 1 hit
PROSITEiView protein in PROSITE
PS00957 NAD_G3PDH, 1 hit

Sequencei

Sequence statusi: Complete.

A3LU81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTPVARLAQ LANILAPNPT AAYAAHSHHP EASLSPEHPF RVAVIGSGNW
60 70 80 90 100
GTTIAKVIAE NAAARPRLFR HQVNMWVHDE IIDGEKLTHI INTRHENVKY
110 120 130 140 150
LPGVILPRNI RAEADIGNVV HDADLIVFNL PHQFLPRVVK SLKGKIKHGA
160 170 180 190 200
RAISCLKGLE VTPEGCKLLS TYITEELGIV CGALSGANIA PEVARCKWSE
210 220 230 240 250
TTVAYKLPED FRGAGKDIDK FVLRACFHRP YFHVNVIEDV AGVSVAGALK
260 270 280 290 300
NVVALAVGFV EGLGWGDNAK AAVMRVGLLE TIKFSETFFP ESIASTFTAE
310 320 330 340 350
SAGVADLITS CSGGRNVKVG RYMAQTGSSA ENAEKMLLNG QSSQGIVTVR
360 370 380 390
EVHDLLTNVG MLDKFPLFEA TYQIIYGSES IENLPLLLVG E
Length:391
Mass (Da):42,235
Last modified:July 24, 2007 - v2
Checksum:i53F144EACAEFFF2C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000498 Genomic DNA Translation: ABN66537.2
RefSeqiXP_001384566.2, XM_001384529.1

Genome annotation databases

EnsemblFungiiABN66537; ABN66537; PICST_83071
GeneIDi4838862
KEGGipic:PICST_83071

Entry informationi

Entry nameiA3LU81_PICST
AccessioniPrimary (citable) accession number: A3LU81
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: July 24, 2007
Last modified: May 23, 2018
This is version 82 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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