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Protein

Histone deacetylase

Gene

PICST_71431

Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

Hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulatorSAAS annotation, HydrolaseSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseSAAS annotation (EC:3.5.1.98SAAS annotation)
Gene namesi
ORF Names:PICST_71431Imported
OrganismiScheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)Imported
Taxonomic identifieri322104 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeScheffersomyces
Proteomesi
  • UP000002258 Componenti: Chromosome 3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi322104.XP_001383345.2

Structurei

3D structure databases

ProteinModelPortaliA3LR32
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini128 – 438Hist_deacetylInterPro annotationAdd BLAST311
Domaini503 – 737Arb2InterPro annotationAdd BLAST235

Phylogenomic databases

eggNOGiKOG1343 Eukaryota
COG0123 LUCA
HOGENOMiHOG000161343
InParanoidiA3LR32
KOiK11407
OMAiCYDDRMK
OrthoDBiEOG092C3GJU

Family and domain databases

Gene3Di3.40.800.20, 1 hit
InterProiView protein in InterPro
IPR019154 Arb2_domain
IPR000286 His_deacetylse
IPR023801 His_deacetylse_dom
IPR037138 His_deacetylse_dom_sf
IPR017321 Hist_deAcase_II_yeast
IPR023696 Ureohydrolase_dom_sf
PANTHERiPTHR10625 PTHR10625, 1 hit
PfamiView protein in Pfam
PF09757 Arb2, 1 hit
PF00850 Hist_deacetyl, 1 hit
PIRSFiPIRSF037919 HDAC_II_yeast, 1 hit
PRINTSiPR01270 HDASUPER
SUPFAMiSSF52768 SSF52768, 1 hit

Sequencei

Sequence statusi: Complete.

A3LR32-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEEPTGVAP ESAPKKRLLE DADTDTKSTS NTSVSGTVEN STDINFHPDT
60 70 80 90 100
NSTEASKGNP DQIPVSNGDD HKRIKLEPKV GNESSIVVVP PTKPQLFYSP
110 120 130 140 150
LKTGLVYDVR MRYHAKIFTS YFEYIDPHPE DPRRIYRIYK KLAEAGLIVD
160 170 180 190 200
SSLSGVEDIG PLMVKIPIRE ATAEEILEVH SESHLKFIQS TETMSRERLL
210 220 230 240 250
EETEKGDSIY VNNDSYFSAK LSCGGTIEAC KAVIEGRVKN SLAIVRPPGH
260 270 280 290 300
HAEPETPGGF CLFSNVAVAA KNILKAYPES VRKIVIVDWD IHHGNGTQKS
310 320 330 340 350
FYDDPRVLYI SLHRYENGRF YPGTKYGGAD QVGEKDGEGY NLNIPWRNPG
360 370 380 390 400
MHDGDYIYAF NRVVLPVILE FDPDLIIVSS GFDAADGDII GGCHVTPAGY
410 420 430 440 450
GYMTHLLKGI AKGKLAVILE GGYNLDSISK SALGVAKVLV GEPPEATVSM
460 470 480 490 500
QPHLETIEVI DEVVKVQSRY WKSLRYGVPT TSFDDVYDLN GTGSNYQLLN
510 520 530 540 550
IGEPIRANQV NELFNKYSFV NLPIISSATE GGEKNGIFST DLPSHLDDII
560 570 580 590 600
IASPDIYEST VVVLTIHDPP EIWANINPIN GSIEGNSSVI LEHPLMQIME
610 620 630 640 650
KMKKETDKSD SKEKIGYIDI NVPSYQLPIP FGNSKQTSTY NPTFFAQELL
660 670 680 690 700
LYIWDNYLAY FSQLKKLVFV GFGDSYQAIV HLYGKRPSQD IKDLVKGTVA
710 720 730 740 750
FVNRSNLKAL VPVMDESMVD WYYQNSVIFT SCSNPCWVNS NGTTRLGNGS
760 770 780 790 800
TEANGGDDSN KRPRRKFGRV LKASVDGLYD IIAERFDEGV DFILDSIEEY

SSSESSN
Length:807
Mass (Da):89,455
Last modified:July 24, 2007 - v2
Checksum:iAF6E4974DE1C5DEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000497 Genomic DNA Translation: ABN65316.2
RefSeqiXP_001383345.2, XM_001383308.1

Genome annotation databases

EnsemblFungiiABN65316; ABN65316; PICST_71431
GeneIDi4838284
KEGGipic:PICST_71431

Similar proteinsi

Entry informationi

Entry nameiA3LR32_PICST
AccessioniPrimary (citable) accession number: A3LR32
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: July 24, 2007
Last modified: March 28, 2018
This is version 72 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health