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A3LP53

- A3LP53_PICST

UniProt

A3LP53 - A3LP53_PICST

Protein

DNA ligase

Gene

PICST_56005

Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 2 (24 Jul 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:PICST_56005Imported
    OrganismiScheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)Imported
    Taxonomic identifieri322104 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeScheffersomyces
    ProteomesiUP000002258: Chromosome 2

    Interactioni

    Protein-protein interaction databases

    STRINGi4924.PICST_56005.

    Structurei

    3D structure databases

    ProteinModelPortaliA3LP53.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    KOiK10747.
    OMAiLDPSGYN.
    OrthoDBiEOG7TXKRG.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A3LP53-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAPRQQSIGR FFGSAMSVDS LLSQTVNKSP KNQKSESLTD EQNKREAFQV    50
    SQQESEKDQE QKPDTDPSES EPEKDKTEEI KEASELIKLS EKEHEKHVGE 100
    KLSAKIPYSK LTDVLDKIEA ESSRLKITAI VSEFFLEILK QSTVDKLVKI 150
    VYLFINRLGP DYEPDLELGL GETILIKAIS ECYGRPSTKI KKDYQEVGDL 200
    GLVAQKSRSG QPTMFKPAPL DVDQVFENLT KIAKSTGKDS QAKKISLINK 250
    MLTACNAKSS EAKFLIRSLE GKLRIGLAEK TVLIGLAQAF VNYEAKDSKR 300
    INPEKLTQSE DVVREAFSQI PNYEILIRNA YEYGIFNLLD HCQLTPGIPL 350
    KPMLAKPTKS ISEVLDRFQG EEFTCEYKYD GERAQVHLLH DGTVRIYSRN 400
    SEDMSERYPD LISIMKDFIK TQEGQAPSMI LDCEAVAWDR VANKILPFQV 450
    LSTRKRKDVD EKDITVHICL FAFDILYFDN EPLITKSLKE RRQVMEENLT 500
    PMDGKFQFAT AKNSSNLDEL QQFLDQSVKD SCEGLMVKML NGKESYYEPS 550
    KRSRNWLKLK KDYLAGVGDS LDLVVIGAYI GRGKRTGNYG GFLLASYNQD 600
    TGEYETTCKI GTGFSDEDLA SLHTKLKPTE ISVPKPYYVY DTTNSNAKPD 650
    VWFEPTTIFE VLTADLSLSP IYKAAHQEYG KGISLRFPRF LRIRDDKGIE 700
    DATSSTQVSE FYERQASVN 719
    Length:719
    Mass (Da):81,417
    Last modified:July 24, 2007 - v2
    Checksum:i7A08F415B801CBEE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000496 Genomic DNA. Translation: ABN64436.2.
    RefSeqiXP_001382465.2. XM_001382428.1.

    Genome annotation databases

    GeneIDi4837358.
    KEGGipic:PICST_56005.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000496 Genomic DNA. Translation: ABN64436.2 .
    RefSeqi XP_001382465.2. XM_001382428.1.

    3D structure databases

    ProteinModelPortali A3LP53.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 4924.PICST_56005.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 4837358.
    KEGGi pic:PICST_56005.

    Phylogenomic databases

    KOi K10747.
    OMAi LDPSGYN.
    OrthoDBi EOG7TXKRG.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545Imported.

    Entry informationi

    Entry nameiA3LP53_PICST
    AccessioniPrimary (citable) accession number: A3LP53
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 3, 2007
    Last sequence update: July 24, 2007
    Last modified: October 1, 2014
    This is version 58 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3