A3L2X4 (A3L2X4_PSEAI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Nicotinate phosphoribosyltransferase 1 HAMAP MF_00570
Short name=NAPRTase 1 HAMAP MF_00570
EC=2.4.2.11 HAMAP MF_00570

Gene names

Name:	pncB1 HAMAP MF_00570
ORF Names:	PACG_04501 EMBL EAZ55805.1

Organism

Pseudomonas aeruginosa C3719 EMBL EAZ55805.1

Taxonomic identifier

350704 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	399 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00570 RuleBase RU003838 SAAS SAAS002638
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP MF_00570 SAAS SAAS002638 Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate ribonucleotide from nicotinate: step 1/1. RuleBase RU003838
Subcellular location	Cytoplasm By similarity HAMAP MF_00570 SAAS SAAS002638.
Sequence similarities	Belongs to the NAPRTase family. HAMAP MF_00570 RuleBase RU003838

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis HAMAP MF_00570 RuleBase RU003838 SAAS SAAS006406
Cellular component	Cytoplasm SAAS SAAS002638 HAMAP MF_00570
Molecular function	Glycosyltransferase HAMAP MF_00570 RuleBase RU003838 SAAS SAAS002638 EMBL EAZ55805.1 Transferase
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: HAMAP nicotinate nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nicotinate phosphoribosyltransferase activity Inferred from electronic annotation. Source: HAMAP nicotinate-nucleotide diphosphorylase (carboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A3L2X4 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: 49B2266CF47346DE	FASTA	399	46,095
	10 20 30 40 50 60 MAESVFAERI VQNLLDTDFY KLTMMQAVLH NYPNAEVEWE FRCRNAEDLR PYLAEIRYQI 70 80 90 100 110 120 ERLAEVEVTA DQLAFLERIP FMKPDFIRFL SLFRFNLRYV HTGIEDGQLA IRLRGPWLHV 130 140 150 160 170 180 ILFEVPLLAI VSEVRNRYRY REVVLEQVGE QLYRKLDWLS AQASSEELAE FQVADFGTRR 190 200 210 220 230 240 RFSYRTQEEV VHILKRDFPG RFVGTSNVHL AREYDLKPIG TMAHEWLMAH QQLGPRLVDS 250 260 270 280 290 300 QQAALDCWVR EYRGQLGIAL TDCITMDAFL DDFDLYFAKL FDGLRHDSGD PLAWAEKAIA 310 320 330 340 350 360 HYRRLGIDPL SKTLVFSDGL DMPKALQLFR ALRGKINVSF GIGTNLTCDI PGVEPMNIVL 370 380 390 KMTACNGHPV AKISDAPGKT QCRDENFVAY LRHVFNVPA

References

[1]

"Dynamics of Pseudomonas aeruginosa genome evolution." Mathee K., Narasimhan G., Valdes C., Qiu X., Matewish J.M., Koehrsen M., Rokas A., Yandava C.N., Engels R., Zeng E., Olavarietta R., Doud M., Smith R.S., Montgomery P., White J.R., Godfrey P.A., Kodira C., Birren B., Galagan J.E., Lory S. Proc. Natl. Acad. Sci. U.S.A. 105:3100-3105(2008) [PubMed: 18287045] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C3719 EMBL EAZ55805.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH482383 Genomic DNA. Translation: EAZ55805.1.
3D structure databases
ProteinModelPortal	A3L2X4.
SMR	A3L2X4. Positions 1-397.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	25572743. VBIPseAer51129_5860.
Phylogenomic databases
OMA	SFGWGTN.
Family and domain databases
HAMAP	MF_00570. NAPRTase. [Tree]
InterPro	IPR006406. Nic_PRibTrfase. IPR015977. Nic_PRibTrfase-like. IPR007229. Nic_PRibTrfase-rel. IPR002638. Quinolinate_PRibosylTrfase_C. [Graphical view]
Pfam	PF04095. NAPRTase. 1 hit. [Graphical view]
PIRSF	PIRSF000484. NAPRT. 1 hit.
SUPFAM	SSF51690. Q_phspho_trans. 1 hit.
TIGRFAMs	TIGR01514. NAPRTase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A3L2X4_PSEAI

Accession

Primary (citable) accession number: A3L2X4

Entry history

Integrated into UniProtKB/TrEMBL:	April 3, 2007
Last sequence update:	April 3, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)