A3KW40 (A3KW40_PSEAI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Beta-hexosaminidase HAMAP MF_00364
EC=3.2.1.52 HAMAP MF_00364

Alternative name(s):
Beta-N-acetylhexosaminidase HAMAP MF_00364
N-acetyl-beta-glucosaminidase HAMAP MF_00364

Gene names

Name:	nagZ HAMAP MF_00364
ORF Names:	PACG_01934 EMBL EAZ53421.1

Organism

Pseudomonas aeruginosa C3719 EMBL EAZ53421.1

Taxonomic identifier

350704 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	332 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides By similarity. HAMAP MF_00364 SAAS SAAS001764
Catalytic activity	Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. HAMAP MF_00364 SAAS SAAS001764
Pathway	Cell wall biogenesis; peptidoglycan recycling. HAMAP MF_00364 SAAS SAAS001764
Subcellular location	Cytoplasm By similarity HAMAP MF_00364 SAAS SAAS001764.
Sequence similarities	Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. HAMAP MF_00364

Ontologies

Keywords
Biological process	Cell cycle Cell division HAMAP MF_00364 SAAS SAAS001764 Cell shape Cell wall biogenesis/degradation HAMAP MF_00364 SAAS SAAS001764 Peptidoglycan synthesis HAMAP MF_00364 SAAS SAAS001764
Cellular component	Cytoplasm HAMAP MF_00364 SAAS SAAS001764
Molecular function	Glycosidase HAMAP MF_00364 SAAS SAAS022956 Hydrolase
Gene Ontology (GO)
Biological process	cell cycle Inferred from electronic annotation. Source: UniProtKB-KW cell division Inferred from electronic annotation. Source: UniProtKB-KW cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan turnover Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	beta-N-acetylhexosaminidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	244	1	By similarity HAMAP MF_00364

Sequences

	Sequence		Length	Mass (Da)
	A3KW40 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: BA472E62B44A097A	FASTA	332	36,101
	10 20 30 40 50 60 MQGSLMLDIG GTWLTAEDRQ ILRHPEVGGL IIFARNIEHP AQVRELCAAI RAIRPDLLLA 70 80 90 100 110 120 VDQEGGRVQR LRQGFVRLPA MRAIADNPNA EELAEHCGWL MATEVQAVGL DLSFAPVLDL 130 140 150 160 170 180 DHQRSAVVGS RAFEGDPERA ALLAGAFIRG MHAAGMAATG KHFPGHGWAE ADSHVAIPED 190 200 210 220 230 240 ARSLEEIRRS DLVPFARLAG QLDALMPAHV IYPQVDPQPA GFSRRWLQEI LRGELKFDGV 250 260 270 280 290 300 IFSDDLSMAG AHVVGDAASR IEAALAAGCD MGLVCNDRAS AELALAALQR LKVTPPSRLQ 310 320 330 RMRGKGYANT DYRQQPRWLE ALSALRAAQL ID

References

[1]

"Dynamics of Pseudomonas aeruginosa genome evolution." Mathee K., Narasimhan G., Valdes C., Qiu X., Matewish J.M., Koehrsen M., Rokas A., Yandava C.N., Engels R., Zeng E., Olavarietta R., Doud M., Smith R.S., Montgomery P., White J.R., Godfrey P.A., Kodira C., Birren B., Galagan J.E., Lory S. Proc. Natl. Acad. Sci. U.S.A. 105:3100-3105(2008) [PubMed: 18287045] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C3719 EMBL EAZ53421.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH482383 Genomic DNA. Translation: EAZ53421.1.
3D structure databases
ProteinModelPortal	A3KW40.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	25567209. VBIPseAer51129_2866.
Phylogenomic databases
OMA	DLTMEGA.
Family and domain databases
HAMAP	MF_00364. NagZ. [Tree]
InterPro	IPR022956. Beta_hexosaminidase. IPR019800. Glyco_hydro_3_AS. IPR001764. Glyco_hydro_3_N. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:3.20.20.300. Glyco_hydro_3_N. 1 hit.
Pfam	PF00933. Glyco_hydro_3. 1 hit. [Graphical view]
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS00775. GLYCOSYL_HYDROL_F3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A3KW40_PSEAI

Accession

Primary (citable) accession number: A3KW40

Entry history

Integrated into UniProtKB/TrEMBL:	April 3, 2007
Last sequence update:	April 3, 2007
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)