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Protein

Secretogranin-3

Gene

scg3

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

ReactomeiR-DRE-114608. Platelet degranulation.

Names & Taxonomyi

Protein namesi
Recommended name:
Secretogranin-3
Alternative name(s):
Secretogranin III
Short name:
SgIII
Gene namesi
Name:scg3
ORF Names:si:ch211-12a1.3, zgc:73236
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 18

Organism-specific databases

ZFINiZDB-GENE-040426-1725. scg3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasmic vesicle, Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence analysisAdd
BLAST
Chaini22 – 478457Secretogranin-3PRO_0000417023Add
BLAST

Keywords - PTMi

Cleavage on pair of basic residues

Proteomic databases

PaxDbiA3KQQ9.
PeptideAtlasiA3KQQ9.

Expressioni

Gene expression databases

BgeeiENSDARG00000086288.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000105698.

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IHUH. Eukaryota.
ENOG4110KQ3. LUCA.
GeneTreeiENSGT00390000005488.
HOGENOMiHOG000247064.
HOVERGENiHBG057085.
InParanoidiA3KQQ9.
OMAiENKPGQS.
OrthoDBiEOG091G06X3.
TreeFamiTF331266.

Family and domain databases

InterProiIPR026197. SCG3.
[Graphical view]
PANTHERiPTHR17388. PTHR17388. 1 hit.
PfamiPF15467. SGIII. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A3KQQ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASKRLGFVV VLALVCQHIN AFPTPAGPDD KYNRELTEEK PLEQQIAEAD
60 70 80 90 100
SIRKTESKPT PPAEEETNSE DDDITFLKAL AEKSKESNNE TPISDSANER
110 120 130 140 150
LGADDTDSTK NRRLADDYDS TKNGMDYKYQ DDPESFRQLD GTPLTAQDIV
160 170 180 190 200
QKIANKIYEE DDRGVFDRIV SKLLKLGLIT DSQAETLEYE VAEALQDLIT
210 220 230 240 250
KNAKDNMIGD RSVDYPVSAA KDTQDEEDRP SPRFDEEDEV ENEGGDDANG
260 270 280 290 300
DEPQEEESRD DTVRSDDSWD AVSDGNDRNE LNPEDGLQDL QFFPNFYRLL
310 320 330 340 350
KSLDSEQDKE ERETLITIMK TLIDFVKMMV KYGTITPEEG VTYLENLDAM
360 370 380 390 400
IALQTKNKLG KSLVPLSITP PTGKAADDDD NTKTEAAKMQ KEYESLKDST
410 420 430 440 450
KDVQTAAEIS HPGKSESYLE AIRKNIEWLK KHNKEGNKED YDLSKLRDFM
460 470
DQQVDSYIDK GILEKDEGDV IKRIYGSL
Length:478
Mass (Da):53,995
Last modified:April 3, 2007 - v1
Checksum:i31688E409CA82429
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti18 – 203HIN → DIS in AAH59577 (Ref. 2) Curated
Sequence conflicti106 – 1061T → A in AAH59577 (Ref. 2) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX927313 Genomic DNA. Translation: CAM56318.1.
BC059577 mRNA. Translation: AAH59577.1.
RefSeqiNP_957051.1. NM_200757.1.
UniGeneiDr.80934.

Genome annotation databases

EnsembliENSDART00000122930; ENSDARP00000105698; ENSDARG00000086288.
GeneIDi393730.
KEGGidre:393730.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX927313 Genomic DNA. Translation: CAM56318.1.
BC059577 mRNA. Translation: AAH59577.1.
RefSeqiNP_957051.1. NM_200757.1.
UniGeneiDr.80934.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000105698.

Proteomic databases

PaxDbiA3KQQ9.
PeptideAtlasiA3KQQ9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000122930; ENSDARP00000105698; ENSDARG00000086288.
GeneIDi393730.
KEGGidre:393730.

Organism-specific databases

CTDi29106.
ZFINiZDB-GENE-040426-1725. scg3.

Phylogenomic databases

eggNOGiENOG410IHUH. Eukaryota.
ENOG4110KQ3. LUCA.
GeneTreeiENSGT00390000005488.
HOGENOMiHOG000247064.
HOVERGENiHBG057085.
InParanoidiA3KQQ9.
OMAiENKPGQS.
OrthoDBiEOG091G06X3.
TreeFamiTF331266.

Enzyme and pathway databases

ReactomeiR-DRE-114608. Platelet degranulation.

Miscellaneous databases

PROiA3KQQ9.

Gene expression databases

BgeeiENSDARG00000086288.

Family and domain databases

InterProiIPR026197. SCG3.
[Graphical view]
PANTHERiPTHR17388. PTHR17388. 1 hit.
PfamiPF15467. SGIII. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSCG3_DANRE
AccessioniPrimary (citable) accession number: A3KQQ9
Secondary accession number(s): Q6PBU8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2012
Last sequence update: April 3, 2007
Last modified: September 7, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.