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A3KQ87

- A3KQ87_DANRE

UniProt

A3KQ87 - A3KQ87_DANRE

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Protein
Submitted name:

Uncharacterized protein

Gene
tgm2l
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

Cofactori

Binds 1 calcium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei274 – 2741 By similarity
Active sitei333 – 3331 By similarityUniRule annotation
Active sitei356 – 3561 By similarity
Metal bindingi396 – 3961Calcium By similarityUniRule annotation
Metal bindingi398 – 3981Calcium By similarityUniRule annotation
Metal bindingi445 – 4451Calcium By similarityUniRule annotation
Metal bindingi450 – 4501Calcium By similarityUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:tgm2lImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 18

Organism-specific databases

ZFINiZDB-GENE-050420-97. tgm2l.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000074762.

Structurei

3D structure databases

ProteinModelPortaliA3KQ87.
SMRiA3KQ87. Positions 6-682.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG80379.
GeneTreeiENSGT00740000115156.
HOVERGENiHBG004342.
InParanoidiA3KQ87.
KOiK05625.
OMAiHAHRTEE.
OrthoDBiEOG72RMXG.
PhylomeDBiA3KQ87.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

A3KQ87-1 [UniParc]FASTAAdd to Basket

« Hide

MASYNAILSD VDLQCYENNH AHRTEEMDVE RLLVRRGQPF SVVLQCTEQI    50
PQLPDHQINL ILHLGKNNEV VLKVSDSEQD PGKWWFSQRN AQGEVMLTLH 100
SPADAPVGLY SMTVVLLSAD GEIQEQTSPQ TFYLLFNPWC KDDCVYLPSE 150
EMLQEYILNE NGILYQGAWD DITTVPWNFG QFEKDVVDIC FDVLDNSPAA 200
LKNSEMDIFN RASPVYVSRT ITAMVNANDD RGVVSGRWDG EYSDGVAPTR 250
WTGSVPILRR WSEDGGQKVR YGQCWVFTGV ACTVLRCLGI PTRCITNYSS 300
AHDTDANIAV DYLVNDQLES VSEGRKDTIW NYHCWVESWM KREDLPEGYD 350
GWQVLDPTPQ ERSDGIFCCG PCPVRAVKEG EVGLKYDTPF VFSEVNADLI 400
VWIVHPDGER SEVSQNSKII GRKISTKSVY GDFREDITAN YKYPEGSMKE 450
REVYKKAGRQ VGQKKDGPGQ LELFIKHAPA IHGTDFDVII EVYNAGREDT 500
DAKLTVTSNA ITYNSIHRGE CQRKTTSLTV PAYKAHKEVL RLQYDHYGAC 550
VSEHHMIRVT ALLQPNDQDN LILQETNIPL KMPALHVKII GNAIVSRKLT 600
AHISFTNPLP INLQGGVFTV EGAGLTEARE IKTHGKIESG QTVTVKFSFK 650
PTRAGLRKLL VDFDSDRLRD VKGEASVIVR TRMRHVNAVP EI 692
Length:692
Mass (Da):77,936
Last modified:April 3, 2007 - v1
Checksum:i3AFEB68748A4CC59
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571681 Genomic DNA. No translation available.
RefSeqiXP_005159207.1. XM_005159150.1.
XP_687398.2. XM_682306.5.

Genome annotation databases

EnsembliENSDART00000142422; ENSDARP00000119989; ENSDARG00000093381.
GeneIDi559012.
KEGGidre:559012.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX571681 Genomic DNA. No translation available.
RefSeqi XP_005159207.1. XM_005159150.1.
XP_687398.2. XM_682306.5.

3D structure databases

ProteinModelPortali A3KQ87.
SMRi A3KQ87. Positions 6-682.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7955.ENSDARP00000074762.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSDART00000142422 ; ENSDARP00000119989 ; ENSDARG00000093381 .
GeneIDi 559012.
KEGGi dre:559012.

Organism-specific databases

CTDi 559012.
ZFINi ZDB-GENE-050420-97. tgm2l.

Phylogenomic databases

eggNOGi NOG80379.
GeneTreei ENSGT00740000115156.
HOVERGENi HBG004342.
InParanoidi A3KQ87.
KOi K05625.
OMAi HAHRTEE.
OrthoDBi EOG72RMXG.
PhylomeDBi A3KQ87.
TreeFami TF324278.

Miscellaneous databases

NextBioi 20882740.
PROi A3KQ87.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.
  2. Ensembl
    Submitted (AUG-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.

Entry informationi

Entry nameiA3KQ87_DANRE
AccessioniPrimary (citable) accession number: A3KQ87
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: July 9, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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