A3KQ12 (A3KQ12_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Protein Wnt RuleBase RU003503

Gene names

Name:	wnt4b Ensembl ENSDARP00000058738 ZFIN ZDB-GENE-000411-1 EMBL AAI62132.1 Ensembl ENSDARP00000100047
ORF Names:	CH211-57K11.8-001 EMBL CAM56525.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL CAM56525.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	358 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Ligand for members of the frizzled family of seven transmembrane receptors By similarity. RuleBase RU003500
Subcellular location	Secreted › extracellular space › extracellular matrix By similarity RuleBase RU003500.
Sequence similarities	Belongs to the Wnt family. RuleBase RU003500

Ontologies

Keywords
Biological process	Wnt signaling pathway SAAS SAAS005817 RuleBase RU003500
Cellular component	Extracellular matrix SAAS SAAS005817 Secreted
Molecular function	Developmental protein SAAS SAAS005817 RuleBase RU003500
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	Wnt receptor signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	proteinaceous extracellular matrix Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	receptor binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A3KQ12 [UniParc]. Last modified April 3, 2007. Version 1. Checksum: D8A6AEB0038341F2	FASTA	358	39,228
	10 20 30 40 50 60 MPTVSSVTLT GRLLLLLLWA AHLAMATNWL SLARLSRSRP VSGAEPCGRL RGLSPGQVGV 70 80 90 100 110 120 CRARGEVMES VRKASEMVIE ECQHQFRNRR WNCSTTPRGI NVFGRVMNQG TREAAFVHAL 130 140 150 160 170 180 SSAAVAVAVT RGCSRGELER CGCDRKVRGV SPEGFQWSGC SDNLSYGVAF SQTFVDEPER 190 200 210 220 230 240 AKGMSSGRPL MNIHNNEAGR KAILHNMQVE CKCHGVSGSC ELRTCWKVMP PFRRVGAVLK 250 260 270 280 290 300 ERFDGATEVR LTRVGSRTAL LPRDPQVKPP ATRDLVYLAP SPDFCRLDPD NGIPGTAGRR 310 320 330 340 350 CNGTSRLAPD GCELLCCGPG FRAGRAEVVQ RCSCKFSWCC SVRCQQCKNT VLIHTCRE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Pooled EMBL AAI62132.1.
[2]	Gray E. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000058738 Ensembl ENSDARP00000100047.
[4]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000058738 Ensembl ENSDARP00000100047.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC162132 mRNA. Translation: AAI62132.1. BC162139 mRNA. Translation: AAI62139.1. BC162540 mRNA. Translation: AAI62540.1. BC162551 mRNA. Translation: AAI62551.1. BX511250 Genomic DNA. Translation: CAM56525.1.
IPI	IPI00487317.
UniGene	Dr.81321.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A3KQ12.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000058739; ENSDARP00000058738; ENSDARG00000040159. ENSDART00000110834; ENSDARP00000100047; ENSDARG00000040159.
Organism-specific databases
ZFIN	ZDB-GENE-000411-1. wnt4b.
Phylogenomic databases
eggNOG	fiNOG14170.
HOGENOM	HBG446188.
HOVERGEN	HBG001595.
InParanoid	A3KQ12.
OMA	QVECKCH.
OrthoDB	EOG4N30P5.
Gene expression databases
Bgee	A3KQ12.
Family and domain databases
InterPro	IPR005817. Wnt. IPR009142. Wnt4. IPR018161. Wnt_grthfactor_CS. [Graphical view]
PANTHER	PTHR12027. Wnt. 1 hit. PTHR12027:SF19. Wnt4. 1 hit.
Pfam	PF00110. wnt. 1 hit. [Graphical view]
PRINTS	PR01349. WNTPROTEIN.
SMART	SM00097. WNT1. 1 hit. [Graphical view]
PROSITE	PS00246. WNT1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A3KQ12_DANRE

Accession

Primary (citable) accession number: A3KQ12

Entry history

Integrated into UniProtKB/TrEMBL:	April 3, 2007
Last sequence update:	April 3, 2007
Last modified:	January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)